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DNMT3L 抗体 (AA 1-387) (FL550)

This anti-DNMT3L antibody is a 小鼠 单克隆 antibody detecting DNMT3L in ICC. Suitable for 人.
产品编号 ABIN7595543
发货至: 中国

Quick Overview for DNMT3L 抗体 (AA 1-387) (FL550) (ABIN7595543)

抗原

See all DNMT3L (TRDMT1) 抗体
DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))

适用

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宿主

  • 70
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小鼠

克隆类型

  • 72
  • 9
单克隆

标记

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This DNMT3L antibody is conjugated to FL550

应用范围

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Immunocytochemistry (ICC)

克隆位点

N117-9
  • 抗原表位

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    AA 1-387

    原理

    Anti-DNMT3L Antibody FL550 Conjugate

    特异性

    No off-targets reported for DNMT3A or DNMT3B

    交叉反应

    产品特性

    Description: Our Anti-DNMT3L mouse monoclonal primary antibody is produced in-house from hybridoma clone N117/9. It detects human DNMT3L, and is purified by Protein A chromatography. It is great for use in ICC.

    Manufacturer Comment: We produce our DNMT3L mouse monoclonal primary antibody from hybridoma clone N117/9. It is great in ICC and is purified by Protein A chromatography.

    纯化方法

    Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

    纯度

    > 90 % specific antibody

    免疫原

    Fusion protein amino acids 1-387 (full-length) of human DNMT3L (accession number BAA95556) produced recombinantly in E. Coli

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    PBS with 0.09 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

    有效期

    12 months
  • 抗原

    DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))

    别名

    DNMT3L

    背景

    Synonyms: DNA (cytosine-5)-methyltransferase 3-like

    Target Description: DNA (cytosine-5)-methyltransferase 3-like or DNMT3L is encoded by the gene DNMT3L. DNMT3l is a nuclear, catalytically inactive, regulatory factor of DNA methyltransferases. DNMT3L mediates transcriptional repression through interaction with histone deacetylase 1. It is thought to be required for the establishment of maternal genomic imprints. DNMT3L is expressed in several tissues including testis, ovary, and thymus. Diseases associated with DNMT3L include Testicular Spermatocytic Seminoma and Immunodeficiency-Centromeric Instability-Facial Anomalies Syndrome.

    Gene Name Alternatives: DNMT3L

    分子量

    45 kDa
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