Ataxin 1 抗体 (AA 746-761) (FL490)
Quick Overview for Ataxin 1 抗体 (AA 746-761) (FL490) (ABIN7595466)
抗原
See all Ataxin 1 (ATXN1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 746-761
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原理
- Anti-Ataxin-1, WT Antibody FL490 Conjugate
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特异性
- Minimal off target reactivity for S751A mutant of Ataxin-1 by ELISA and immunofluorescence and negative by immunoblot (right)
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Description: Our Anti-Ataxin-1, WT mouse monoclonal primary antibody is produced in-house from hybridoma clone N65/37. It detects human, mouse, and rat Ataxin-1, WT, and is purified by Protein A chromatography. It is great for use in ICC.
Manufacturer Comment: We produce our Ataxin-1, WT mouse monoclonal primary antibody from hybridoma clone N65/37. It is great in ICC and is purified by Protein A chromatography.
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纯化方法
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.
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纯度
- > 90 % specific antibody
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免疫原
- Synthetic peptide amino acids 746-761 (RKRRRWSAPETRKLEK) of mouse ataxin-1 (accession number P54254)
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- PBS with 0.09 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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有效期
- 12 months
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- Ataxin 1 (ATXN1)
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别名
- Ataxin-1
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背景
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Synonyms: Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog)
Target Description: Ataxin1, also known as spinocerebellar ataxia type 1 protein homolog, is a highly conserved DNA-binding protein. Ataxin1 is expressed in brain and can be found at high levels in the cortex and the hypothalamus in neurons. It is also expressed in other tissues. Within the cell, it is highly expressed in the nucleus, and can also be found in the cytoplasm. Mutations in the ataxin-1 gene cause spinocerebellar ataxia type 1.
Gene Name Alternatives: Atxn1 Sca1
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分子量
- 85 kDa
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途径
- Synaptic Membrane
抗原
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