MFN1 抗体 (AA 350-580) (FL490)
Quick Overview for MFN1 抗体 (AA 350-580) (FL490) (ABIN7595446)
抗原
See all MFN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 350-580
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原理
- Anti-Mitofusin-1 Antibody FL490 Conjugate
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特异性
- No off-targets reported for Mitofusin-2
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交叉反应
- 小鼠, 大鼠
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产品特性
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Description: Our Anti-Mitofusin-1 mouse monoclonal primary antibody is produced in-house from hybridoma clone N111/24. It is KO validated, detects mouse and rat Mitofusin-1, and is purified by Protein A chromatography. It is great for use in ICC.
Manufacturer Comment: We produce our Mitofusin-1 mouse monoclonal primary antibody from hybridoma clone N111/24. It is great in ICC and is purified by Protein A chromatography.
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纯化方法
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.
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纯度
- > 90 % specific antibody
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免疫原
- Fusion protein amino acids 350-580 of mouse Mitofusin-1 (accession number Q811U4) produced recombinantly in E. Coli
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- PBS with 0.09 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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有效期
- 12 months
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- MFN1 (Mitofusin 1 (MFN1))
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别名
- Mitofusin-1
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背景
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Synonyms: Mitofusin-1 (EC 3.6.5.-) (Transmembrane GTPase MFN1)
Target Description: Mitofusin 1, or transmembrane GTPase Mfn1 (MFN1) is a mitochondrial membrane protein with GTPase activity that functions to aid mitochondrial clustering and fusion. It may also play a role in mitochondrial metabolism. It is expressed in the outer membrane of mitochondria in many tissues, including heart and testis. Diseases associated with MFN1 include Optic Atrophy 1 and Autosomal Recessive Spastic Paraplegia .
Gene Name Alternatives: Mfn1
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分子量
- 80 kDa
抗原
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