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CoREST 抗体 (AA 109-293) (FL490)

This anti-CoREST antibody is a 小鼠 单克隆 antibody detecting CoREST in IHC 和 ICC. Suitable for 人.
产品编号 ABIN7595422
发货至: 中国

Quick Overview for CoREST 抗体 (AA 109-293) (FL490) (ABIN7595422)

抗原

See all CoREST (RCOR1) 抗体
CoREST (RCOR1) (REST Corepressor 1 (RCOR1))

适用

  • 42
  • 10
  • 4
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  • 3
  • 3
  • 2
  • 2
  • 1
  • 1

宿主

  • 38
  • 4
  • 1
小鼠

克隆类型

  • 36
  • 7
单克隆

标记

  • 25
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This CoREST antibody is conjugated to FL490

应用范围

  • 28
  • 18
  • 14
  • 8
  • 5
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  • 2
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Immunocytochemistry (ICC)

克隆位点

K72-8
  • 抗原表位

    • 8
    • 6
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    AA 109-293

    原理

    Anti-Co-Rest/RCOR1 Antibody FL490 Conjugate

    特异性

    No off-targets reported

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Description: Our Anti-Co-Rest/RCOR1 mouse monoclonal primary antibody is produced in-house from hybridoma clone K72/8. It detects human, mouse, and rat Co-Rest/RCOR1, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

    Manufacturer Comment: We produce our Co-Rest/RCOR1 mouse monoclonal primary antibody from hybridoma clone K72/8. It is great in IHC, ICC and is purified by Protein A chromatography.

    纯化方法

    Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

    纯度

    > 90 % specific antibody

    免疫原

    Fusion protein amino acids 109-293 of human Co-Rest (accession number Q9UKL0), includes ELM2 and SANT domains, produced recombinantly in E. Coli

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    PBS with 0.09 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

    有效期

    12 months
  • 抗原

    CoREST (RCOR1) (REST Corepressor 1 (RCOR1))

    别名

    RCOR1

    背景

    Synonyms: REST corepressor 1 (Protein CoREST)

    Target Description: REST Corepressor 1, CoREST or RCOR is encoded by the gene RCOR1 and is a member of the CoREST family of proteins. CoREST is a corepressor to the RE1 silencing transcription factor/neural restrictive silencing (REST) transcription factor and is part of a multiprotein complex (BHC complex) that represses transcription of neuron-specific genes in non-neuronal cells. This complex determines neural cell differentiation. CoREST is ubiquitously expressed in the nucleus of cells. Diseases associated with this gene include Huntington Disease and Loeys-Dietz Syndrome 1.

    Gene Name Alternatives: RCOR1 KIAA0071 RCOR

    分子量

    66-80 kDa (depending on gel system used)

    途径

    Regulation of Hormone Metabolic Process, Chromatin Binding
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