DREAM 抗体 (AA 1-256) (FL490)
Quick Overview for DREAM 抗体 (AA 1-256) (FL490) (ABIN7595409)
抗原
See all DREAM (KCNIP3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-256
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原理
- Anti-KChIP3 K+ Channel Antibody FL490 Conjugate
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特异性
- No off-targets reported for rat KChIPs 1,2, 4
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Description: Our Anti-KChIP3 K+ channel mouse monoclonal primary antibody is produced in-house from hybridoma clone K66/38. It is KO validated, detects human, mouse, and rat KChIP3 K+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
Manufacturer Comment: We produce our KChIP3 K+ channel mouse monoclonal primary antibody from hybridoma clone K66/38. It is great in IHC, ICC and is purified by Protein A chromatography.
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纯化方法
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.
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纯度
- > 90 % specific antibody
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免疫原
- Fusion protein amino acids 1-256 (full length) of rat Calsenillin/DREAM/KChIP3 (accession number Q9JM47) produced recombinantly in E. Coli
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- PBS with 0.09 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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有效期
- 12 months
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- DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))
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别名
- KChIP3 K+ channel
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背景
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Synonyms: Calsenilin (A-type potassium channel modulatory protein 3) (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (KChIP3)
Target Description: Kchip3 potassium channel, also known as Kv channel-interacting protein 3, Kcnip3, DREantagonist modulator and Dream is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin or neuronal calcium sensor (NCS) family branch of the EF-hand superfamily. Kchip3 is an integral subunit component of native Kv4 channel complexes that may regulate A-type currents and function as a calcium regulated transcriptional repressor. Kchip3 is detected in brain, specifically in the cortex, thalamus, dentate gyrus and cerebellum and can be found throughout the cell. It is also found in other tissues at low levels. Diseases associated with KCNIP3 include alzheimer disease.
Gene Name Alternatives: Kcnip3 Csen Dream Kchip3
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分子量
- 34 kDa
抗原
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