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DREAM 抗体 (N-Term)

KCNIP3 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN357125
发货至: 中国
  • 抗原 See all DREAM (KCNIP3) 抗体
    DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))
    抗原表位
    • 10
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    适用
    • 55
    • 31
    • 21
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 48
    • 6
    • 2
    克隆类型
    • 53
    • 3
    多克隆
    标记
    • 28
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DREAM antibody is un-conjugated
    应用范围
    • 51
    • 26
    • 22
    • 13
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects KChIP3 at N-term.
    纯化方法
    Protein GChromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of Human KChIP3. Genename: KCNIP3
    亚型
    Ig Fraction
    Top Product
    Discover our top product KCNIP3 Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry on Paraffin Sections 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C fore month or (in aliquots) at-20 °C for longer.
  • 抗原
    DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))
    别名
    Calsenilin (KCNIP3 产品)
    背景
    KChIP3 is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease. Due to utilization of an alternate in-frame translation start codon, the gene for this protein encodes two isoforms with different sizes.Synonyms: A-type potassium channel modulatory protein 3, CSEN, DRE-antagonist modulator, DREAM, KCHIP3, KCNIP3, Kv channel-interacting protein 3
    分子量
    29231 Da
    基因ID
    30818, 9606
    UniProt
    Q9Y2W7
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