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IL2 Receptor beta 抗体 (FITC)

The 小鼠 单克隆 anti-IL2 Receptor beta antibody is suitable to detect IL2 Receptor beta in samples from 人. It has been validated for FACS.
产品编号 ABIN7595394
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
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Quick Overview for IL2 Receptor beta 抗体 (FITC) (ABIN7595394)

抗原

See all IL2 Receptor beta (IL2RB) 抗体
IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL2 Receptor beta antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

TU27
  • 原理

    Anti-Hu CD122 FITC

    产品特性

    The mouse monoclonal antibody TU27 recognizes an extracellular epitope of CD122 (IL-2R beta), a 70-75 kDa type I transmembrane glycoprotein constitutively expressed by NK cells and a T cell subset, and upregulated upon activation.

    纯化方法

    Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    TL-Mor cell line

    亚型

    IgG1, kappa
  • 应用备注

    Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze,Protect from prolonged exposure to light

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原

    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

    别名

    CD122

    背景

    CD122 (IL-2/IL-15R beta) constitutes together with CD132 (common gamma chain) and with CD25 (IL-2/IL15R alpha) the intermediate (CD122+CD132) and the high affinity (CD122+CD132+CD25) IL-2 and IL-15 receptor complex. CD122 is expressed on NK cells and lymphocytes, but at low level, unless the cell is activated. The cytoplasmic part of CD122 binds to Src-family and Jak-family kinases. The biological effect of CD122 ligation depends on whether IL-2 or IL-15 is bound to the receptor complex.

    基因ID

    3560

    UniProt

    P14784

    途径

    JAK/STAT Signaling, Growth Factor Binding
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