CD276 抗体
Quick Overview for CD276 抗体 (ABIN7595384)
抗原
See all CD276 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD276 Purified
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特异性
- The mouse monoclonal antibody 7-517 recognizes an extracellular epitope of human CD276 (B7H3) transmembrane glycoprotein.
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纯化方法
- Purified by protein-A affinity chromatography.
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免疫原
- monocyte-derived dendritic cells
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亚型
- IgG1 kappa
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应用备注
- Flow cytometry: Recommended dilution: 0.5-4 μg/mL.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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- CD276
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别名
- CD276
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背景
- CD274 Molecule,CD274 / PD-L1 (programmed death ligand-1), also known as B7-H1, is a member of the B7 family of regulatory proteins. It can act as both costimulatory and coinhibitory molecule for T cells. Interaction with its receptor CD279 (PD1) appears to be important in the maintenance of peripheral tolerance and in prevention of tumor rejection. Even pathogens (e.g. Schistosoma) may exploit CD274 to evade an immune response. Besides CD279, existence of other receptor(s) for CD274 is likely.,B7H1, PDL1, PDCD1L1, PDCD1LG1, PDCD1 ligand 1, B7-H1
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基因ID
- 80381
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UniProt
- Q5ZPR3
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途径
- Cancer Immune Checkpoints
抗原
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