Hemagglutinin 抗体
Quick Overview for Hemagglutinin 抗体 (ABIN7595337)
抗原
See all Hemagglutinin (HA) 抗体适用
宿主
克隆类型
标记
应用范围
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Virus Strain
- A/Singapore/1/1957
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原理
- Rabbit antibody to Influenza A virus HA (25...515)
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特异性
- Specific for Influenza A virus HA.
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交叉反应
- Influenza A Virus
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纯化方法
- Purified IgG
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免疫原
- A chimeric recombinant hemagglutinin from Influenza A virus (strain A/Singapore/1/1957 H2N2) containing regions 25-56 110-140 194-232 365-423 443-472 and 490-515 was used as the antigen.
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亚型
- IgG
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anti-Hemagglutinin antibody (Influenza A Virus) (AA 128-143)
HA 适用: Influenza A Virus WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hemagglutinin antibody (Influenza A Virus H9N2) (AA 9-28)HA 适用: Influenza A Virus H9N2 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hemagglutinin antibody (Influenza A Virus H1N1 (A/California/04/2009)) (AA 151-250)HA 适用: Influenza A Virus H1N1, Virus ELISA, WB, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hemagglutinin antibody (Influenza A Virus) (AA 17-338)HA 适用: Influenza A Virus WB 宿主: 小鼠 Monoclonal 4E10C10 unconjugated
anti-Hemagglutinin antibody (Influenza Virus)HA 适用: Influenza Virus ELISA, IP, WB, DB 宿主: 小鼠 Monoclonal HA-C5 unconjugated
anti-Hemagglutinin antibody (Influenza A Virus H3N2 (A/Shangdong/9/93))HA 适用: Influenza A Virus H3N2 ELISA, WB 宿主: 小鼠 Monoclonal B264M unconjugated
anti-Hemagglutinin antibody (Influenza A Virus) (AA 72-88)HA 适用: Influenza A Virus WB 宿主: 兔 Polyclonal unconjugated
anti-Hemagglutinin antibody (Influenza A Virus H1N1 (A/Swine/Iowa/15/1930 H1N1)) (AA 205-220)HA 适用: Influenza A Virus H1N1 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC WB ELISA. A dilution of 1 : 1000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8C for a shorter term.
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有效期
- 12 months
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- Hemagglutinin (HA)
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别名
- Hemagglutinin
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物质类
- Influenza Protein
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背景
- Hemagglutinin: Major glycoprotein comprises over 80 % of the envelope proteins present in virus particle. The extent of infection into host organism is determined by HA. Influenza viruses bud from the apical surface of polarized epithelial cells (e.g. bronchial epithelial cells) into lumen of lungs and are therefore usually pneumotropic. The reason is that HA is cleaved by tryptase clara which is restricted to lungs. However HAs of H5 and H7 pantropic avian viruses subtypes can be cleaved by furin and subtilisin-type enzymes allowing the virus to grow in other organs than lungs. FUNCTION: Binds to sialic acid-containing receptors on the cell surface bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2 releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.
抗原
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