NOS1 抗体
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北京 101111
Quick Overview for NOS1 抗体 (ABIN7595322)
抗原
See all NOS1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Chicken antibody to nNOS
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特异性
- Specific for nNOS
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交叉反应
- 人, Marmoset, 小鼠, 大鼠
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交叉反应 (详细)
- Other species not yet tested.
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纯化方法
- Purified IgY
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免疫原
- A synthetic peptide from human nNOS conjugated to blue carrier protein was used as the antigen. The peptide is homologous in mouse and shares 96% identity with rat's sequence.
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亚型
- IgY
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应用备注
- IHC WB. A dilution of 1: 500 is recommended. The optimal dilution should be determined by the end user.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8C for a shorter term.
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有效期
- 12 months
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- NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))
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别名
- nNOS
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背景
- FUNCTION: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system NO displays many properties of a neurotransmitter. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum. SUBCELLULAR LOCATION: Cell membrane sarcolemma, Peripheral membrane protein. Cell projection dendritic spine. Note=In skeletal muscle it is localized beneath the sarcolemma of fast-twitch muscle fiber by associating with the dystrophin glycoprotein complex. In neurons enriched in dendritic spines. TISSUE SPECIFICITY: Isoform N-NOS-1 is expressed in brain and colorectum. Found in the Auerbach's plexus of the enteric nervous system. Isoform PNNOS is expressed in the penis urethra prostate and skeletal muscle and coexists with the cerebellar nnos in the pelvic plexus bladder and liver and is detectable in the cerebellum.
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途径
- Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction
抗原
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