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NOS1 抗体

The 小鸡 多克隆 anti-NOS1 antibody is suitable to detect NOS1 in samples from 人. It has been validated for WB 和 IHC.
产品编号 ABIN7595322
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for NOS1 抗体 (ABIN7595322)

抗原

See all NOS1 抗体
NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))

适用

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宿主

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小鸡

克隆类型

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多克隆

标记

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This NOS1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 原理

    Chicken antibody to nNOS

    特异性

    Specific for nNOS

    交叉反应

    人, Marmoset, 小鼠, 大鼠

    交叉反应 (详细)

    Other species not yet tested.

    纯化方法

    Purified IgY

    免疫原

    A synthetic peptide from human nNOS conjugated to blue carrier protein was used as the antigen. The peptide is homologous in mouse and shares 96% identity with rat's sequence.

    亚型

    IgY
  • 应用备注

    IHC WB. A dilution of 1: 500 is recommended. The optimal dilution should be determined by the end user.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8C for a shorter term.

    有效期

    12 months
  • 抗原

    NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))

    别名

    nNOS

    背景

    FUNCTION: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system NO displays many properties of a neurotransmitter. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum. SUBCELLULAR LOCATION: Cell membrane sarcolemma, Peripheral membrane protein. Cell projection dendritic spine. Note=In skeletal muscle it is localized beneath the sarcolemma of fast-twitch muscle fiber by associating with the dystrophin glycoprotein complex. In neurons enriched in dendritic spines. TISSUE SPECIFICITY: Isoform N-NOS-1 is expressed in brain and colorectum. Found in the Auerbach's plexus of the enteric nervous system. Isoform PNNOS is expressed in the penis urethra prostate and skeletal muscle and coexists with the cerebellar nnos in the pelvic plexus bladder and liver and is detectable in the cerebellum.

    途径

    Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction
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