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NOS1 抗体 (C-Term)

NOS1 适用: 人 WB, IHC 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN350524
发货至: 中国
  • 抗原 See all NOS1 抗体
    NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))
    抗原表位
    • 27
    • 15
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    C-Term
    适用
    • 126
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    • 15
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    宿主
    • 134
    • 20
    • 2
    山羊
    克隆类型
    • 127
    • 29
    多克隆
    标记
    • 68
    • 20
    • 11
    • 6
    • 4
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    This NOS1 antibody is un-conjugated
    应用范围
    • 116
    • 61
    • 46
    • 31
    • 28
    • 27
    • 26
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    • 12
    • 8
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    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    Specific for nNOS
    交叉反应
    豚鼠, 人, 小鼠, 兔, 大鼠
    交叉反应 (详细)
    Other species not yet tested.
    纯化方法
    IgG
    免疫原
    Synthetic peptides from the c-terminal region of human nNOS conjugated to blue carrier protein was used as the antigen.
    亚型
    IgG
    Top Product
    Discover our top product NOS1 Primary Antibody
  • 应用备注
    IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
    注意事项
    Avoid freeze and thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    有效期
    12 months
  • 抗原
    NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))
    别名
    NOS1 (NOS1 产品)
    别名
    NOS1 antibody, IHPS1 antibody, N-NOS antibody, NC-NOS antibody, NOS antibody, bNOS antibody, nNOS antibody, 2310005C01Rik antibody, NO antibody, NOS-I antibody, Nos-1 antibody, nos antibody, ihps1 antibody, nnos antibody, nos1 antibody, nos1-A antibody, nanos C2HC-type zinc finger 1 antibody, nitric oxide synthase 1 antibody, nitric oxide synthase 1, neuronal antibody, nitric oxide synthase 1 (neuronal) antibody, nitric oxide synthase 1 L homeolog antibody, NANOS1 antibody, NOS1 antibody, Nos1 antibody, nos1 antibody, nos1.L antibody
    背景
    FUNCTION: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum. CATALYTIC ACTIVITY: L-arginine + n NADPH + m O2 = citrulline + nitric oxide + n NADP+. ENZYME REGULATION: Stimulated by calcium/calmodulin. Inhibited by n-Nos-inhibiting protein (PIN) which may prevent the dimerization of the protein. Inhibited by NOSIP. SUBCELLULAR LOCATION: Cell membrane, sarcolemma, Peripheral membrane protein. Cell projection, dendritic spine. Note=In skeletal muscle, it is localized beneath the sarcolemma of fast-twitch muscle fiber by associating with the dystrophin glycoprotein complex. In neurons, enriched in dendritic spines. TISSUE SPECIFICITY: Isoform N-NOS-1 is expressed in brain and colorectum. Found in the Auerbach's plexus of the enteric nervous system. Isoform PNNOS is expressed in the penis, urethra, prostate, and skeletal muscle, and coexists with the cerebellar nnos in the pelvic plexus, bladder and liver, and is detectable in the cerebellum.,Neurotransmission,BNOS, NOS type I, Neuronal NOS, N-NOS, nNOS, Constitutive NOS, NC-NOS, Nitric oxide synthase
    UniProt
    P29476
    途径
    Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction
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