HTR2A 抗体 (Extracellular)
Quick Overview for HTR2A 抗体 (Extracellular) (ABIN7581898)
抗原
See all HTR2A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 40-52, Extracellular
-
原理
- A Guinea Pig Polyclonal Antibody to 5-HT2A Receptor
-
序列
- (C)SEASNWTIDA ENR
-
特异性
- Extracellular, N-terminus
-
预测反应
- Mouse - identical, human - 9 out of 13 amino acid residues identical
-
产品特性
- Guinea Pig Anti-5HT2A Receptor (HTR2A) (extracellular) Antibody (ABIN7581898) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize 5-HT2A from mouse, rat and human samples. The antigen used to immunize guinea pigs is the same as Anti-5HT2A Receptor (HTR2A) (extracellular) (ABIN7042875, ABIN7045286 and ABIN7045287) raised in rabbit. Our line of guinea pig antibodies enables more flexibility with our products such as multiplex staining studies, immunoprecipitation and more.
-
纯化方法
- Affinity purified on immobilized antigen.
-
免疫原
- (C)SEASNWTIDAENR, corresponding to amino acid residues 40-52 of rat 5-Hydroxytryptamine receptor 2A
-
亚型
- IgG
-
-
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (AA 65-160) antibody
HTR2A 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (AA 51-150) antibodyHTR2A 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (AA 296-309) antibodyVerified HTR2A 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (AA 385-471) antibodyHTR2A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (N-Term) antibodyHTR2A 适用: 人, Pig, Bat, 马 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (AA 40-52), (Extracellular) antibodyHTR2A 适用: 大鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (AA 16-30), (N-Term) antibodyHTR2A 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB52772 unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (AA 21-120) antibodyHTR2A 适用: 小鼠, 大鼠 ELISA, IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (AA 171-270) antibodyHTR2A 适用: 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (N-Term) antibodyHTR2A 适用: 人, 小鼠, Pig, Cow WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:400
Application Dilutions Western blot wb: 1:200
-
说明
-
Negative Control: (ABIN7234591)
Blocking Peptide: (ABIN7234591)
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- 0.2 mL double distilled water (DDW).
-
浓度
- 1 mg/mL
-
缓冲液
- PBS pH 7.4
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
-
-
- HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))
-
别名
- HTR2A
-
背景
- 5-Hydroxytryptamine receptor 2A, Serotonin receptor 2A, 5-HT2A,5-HT is involved in a diverse array of physiological and biological processes. In the brain, 5-HT affects sleep, mood, appetite, anxiety, aggression, perception, pain, and cognition1. Signaling of 5-HT is mediated by receptors that are located on the cell membrane of neurons and most other cells in the body. The 5-HT2 family consists of three G-protein coupled receptors (GPCRs): 5-HT2A, 5-HT2B, and 5-HT2C2. They are transmembrane proteins consisting of seven membrane-spanning α-helical segments with an extracellular N-terminus and an intracellular C-terminus. The binding of 5-HT to one of its receptors is thought to elicit a conformational change that activates associated heterotrimeric G proteins and recruits other downstream signaling/scaffolding molecules, such as GPCR kinases and β-arrestins.5-HT2A receptors have been found in many regions of the human brain including the cortex, brainstem, olfactory bulb, limbic system and basal ganglia3.The 5-HT2A receptor has been implicated in many mental disorders including schizophrenia, depression, obsessive compulsive disorder (OCD), attention deficit-hyperactivity disorder (ADHD), and eating disorders such as anorexia nervosa and autism spectrum disorders4.
-
基因ID
- 29595
-
UniProt
- P14842
-
途径
- JAK/STAT Signaling, Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process
抗原
-
