Recombinant CRP 抗体
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北京 101111
Quick Overview for Recombinant CRP 抗体 (ABIN7581768)
抗原
See all CRP 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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Expression System
- Phage display
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原理
- Mouse Anti- human C-reactive protein (CRP)
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特异性
- This is an antibody developed by antibody phage display technology using a human naive antibody gene library and human C-reactive protein (CRP) antigen. For this antibody both the heavy and light chains are cloned and expressed, generating full-length antibodies.
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产品特性
- This antibody can be detected with anti-mouse Fc secondary antibodies.
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纯化方法
- Protein A purification
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免疫原
- No immunization, animal-free antibody development. Antigen: human C-reactive protein
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亚型
- IgG2a
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anti-C-Reactive Protein (CRP) (AA 17-224) antibody
CRP 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-C-Reactive Protein (CRP) (AA 1-224) antibodyCRP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-C-Reactive Protein (CRP) (AA 20-222) antibodyCRP 适用: Pig WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-C-Reactive Protein (CRP) (AA 14-224) antibodyCRP 适用: Cow WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-C-Reactive Protein (CRP) antibodyCRP 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1G1 unconjugated
anti-C-Reactive Protein (CRP) (AA 20-225) antibodyCRP 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-C-Reactive Protein (CRP) (Internal Region) antibodyCRP 适用: 人, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-C-Reactive Protein (CRP) (AA 125-224) antibodyCRP 适用: 人, 小鼠, 兔 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-C-Reactive Protein (CRP) antibodyCRP 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-C-Reactive Protein (CRP) (AA 20-230) antibodyCRP 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA: 1-12 μg/mL as coating antibody 0.5-5 μg/mL as detection antibody Optimal working dilution should be determined by the investigator
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4,
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储存条件
- -20 °C
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- CRP (C-Reactive Protein (CRP))
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别名
- C-reactive Protein
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背景
- C-reactive protein (CRP) is an important acute-phase protein produced by the liver in response to inflammation, primarily triggered by the cytokine interleukin-6 (IL-6). Structurally, CRP is a pentamer composed of five identical subunits, which enables it to bind to phosphocholine on the surfaces of dead or dying cells and certain bacteria. This binding facilitates the activation of the complement system and enhances phagocytosis, playing a crucial role in the innate immune response. Clinically, elevated CRP levels in the blood serve as a non-specific marker of inflammation, making it useful for diagnosing and monitoring conditions such as infections, autoimmune disorders, and inflammatory diseases like rheumatoid arthritis and inflammatory bowel disease (IBD). High-sensitivity CRP (hs-CRP) tests are also utilized to assess the risk of cardiovascular diseases, including heart attacks and strokes, by detecting low levels of chronic inflammation. In summary, C-reactive protein is a key indicator of inflammation and immune system activity, widely used in medical diagnostics to evaluate and monitor various inflammatory and infectious conditions.
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分子量
- 115 kDa
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基因ID
- 1401
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NCBI登录号
- NG_013007
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UniProt
- P02741
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途径
- Carbohydrate Homeostasis
抗原
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