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Recombinant CRP 抗体

This anti-CRP antibody is a 小鼠 单克隆 antibody detecting CRP in ELISA. Suitable for 人.
产品编号 ABIN7581768
发货至: 中国

Quick Overview for Recombinant CRP 抗体 (ABIN7581768)

抗原

See all CRP 抗体
CRP (C-Reactive Protein (CRP))

抗体类型

Recombinant Antibody

适用

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小鼠

克隆类型

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单克隆

标记

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This CRP antibody is un-conjugated

应用范围

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ELISA

质量等级

Animal-Free

克隆位点

AB469-1-A05
  • Expression System

    Phage display

    原理

    Mouse Anti- human C-reactive protein (CRP)

    特异性

    This is an antibody developed by antibody phage display technology using a human naive antibody gene library and human C-reactive protein (CRP) antigen. For this antibody both the heavy and light chains are cloned and expressed, generating full-length antibodies.

    产品特性

    This antibody can be detected with anti-mouse Fc secondary antibodies.

    纯化方法

    Protein A purification

    免疫原

    No immunization, animal-free antibody development. Antigen: human C-reactive protein

    亚型

    IgG2a
  • 应用备注

    ELISA: 1-12 μg/mL as coating antibody 0.5-5 μg/mL as detection antibody Optimal working dilution should be determined by the investigator

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4,

    储存条件

    -20 °C
  • 抗原

    CRP (C-Reactive Protein (CRP))

    别名

    C-reactive Protein

    背景

    C-reactive protein (CRP) is an important acute-phase protein produced by the liver in response to inflammation, primarily triggered by the cytokine interleukin-6 (IL-6). Structurally, CRP is a pentamer composed of five identical subunits, which enables it to bind to phosphocholine on the surfaces of dead or dying cells and certain bacteria. This binding facilitates the activation of the complement system and enhances phagocytosis, playing a crucial role in the innate immune response. Clinically, elevated CRP levels in the blood serve as a non-specific marker of inflammation, making it useful for diagnosing and monitoring conditions such as infections, autoimmune disorders, and inflammatory diseases like rheumatoid arthritis and inflammatory bowel disease (IBD). High-sensitivity CRP (hs-CRP) tests are also utilized to assess the risk of cardiovascular diseases, including heart attacks and strokes, by detecting low levels of chronic inflammation. In summary, C-reactive protein is a key indicator of inflammation and immune system activity, widely used in medical diagnostics to evaluate and monitor various inflammatory and infectious conditions.

    分子量

    115 kDa

    基因ID

    1401

    NCBI登录号

    NG_013007

    UniProt

    P02741

    途径

    Carbohydrate Homeostasis
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