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ENPP2 抗体

ENPP2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN7581209
发货至: 中国
  • 抗原 See all ENPP2 抗体
    ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))
    适用
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    宿主
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    山羊
    克隆类型
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    多克隆
    标记
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    This ENPP2 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA
    原理
    Goat polycolonal antibody targeting human Autotaxin (ATX)
    特异性
    Anti-ATX antibody recognizes endogenous human ATX and is predicted to recognize rat, mouse, horse, and feline ATX based on amino acid conservation.
    纯化方法
    affinity purified
    免疫原
    ATX peptide
    亚型
    IgG
    Top Product
    Discover our top product ENPP2 Primary Antibody
  • 应用备注
    WB – 1:1000, ELISA – 1:1000 Other in vitro and cellular applications are possible using this antibody, but have not been verified.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4
    储存条件
    4 °C,-20 °C
    储存方法
    Antibody is stable for up to 1 year at -20°C. Antibody is stable at 4°C for up to 60 days. Avoid repeated freeze/thaw cycles.
  • 抗原
    ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))
    别名
    Autotaxin (ENPP2 产品)
    背景
    ATX, also known as ENPP2, cleaves choline from lysophosphatidylcholine forming lysophosphatidic acid (LPA), a potent mitogen that has been implicated in the pathophysiology of ovarian cancer. ATX has been demonstrated to increase cell motility, neovascularization, proliferation, and aggressiveness of tumors and is upregulated in numerous cancer lineages (non-small cell lung , glioma, mammary carcinoma, renal cell carcinoma, hepatocellular carcinoma). In addition, dysregulation of the ATX/LPA pathway is central to the pathophysiology of idiopathic pulmonary fibrosis, rheumatoid arthritis, and other inflammatory diseases.
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