NGFR 抗体 (AA 301-400) (FITC)
Quick Overview for NGFR 抗体 (AA 301-400) (FITC) (ABIN725667)
抗原
See all NGFR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-400
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Pig,Horse,Guinea Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from rat NGFR
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亚型
- IgG
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应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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Exendin-4 promotes proliferation of adipose-derived stem cells through ERK and JNK signaling pathways." in: In vitro cellular & developmental biology. Animal, Vol. 52, Issue 5, pp. 598-606, (2016) (PubMed).
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Exendin-4 promotes proliferation of adipose-derived stem cells through ERK and JNK signaling pathways." in: In vitro cellular & developmental biology. Animal, Vol. 52, Issue 5, pp. 598-606, (2016) (PubMed).
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- NGFR (Nerve Growth Factor Receptor (NGFR))
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别名
- p75 NGF Receptor
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背景
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Synonyms: p75, LNGFR, p75NTR, RNNGFRR, Tnfrsf16, Tumor necrosis factor receptor superfamily member 16, Gp8-LNGFR, Low affinity neurotrophin receptor p75NTR, Low-affinity nerve growth factor receptor, NGF receptor, p75 ICD, CD271, Ngfr
Background: Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake. Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.
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基因ID
- 24596
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UniProt
- P07174
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途径
- NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
抗原
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