Caspase 10 抗体 (AA 431-521) (Cy7)
Quick Overview for Caspase 10 抗体 (AA 431-521) (Cy7) (ABIN724781)
抗原
See all Caspase 10 (CASP10) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 431-521
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交叉反应
 - 人
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纯化方法
 - Purified by Protein A.
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免疫原
 - KLH conjugated synthetic peptide derived from human Caspase-10
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亚型
 - IgG
 
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应用备注
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                        FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 
                                            
限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 1 μg/μL
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缓冲液
 - Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
 - ProClin
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注意事项
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
 - -20 °C
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储存方法
 - Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
 - 12 months
 
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- Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
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别名
 - Caspase-10
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背景
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Synonyms: MCH4, ALPS2, FLICE2, Caspase-10, CASP-10, Apoptotic protease Mch-4, FAS-associated death domain protein interleukin-1B-converting enzyme 2, ICE-like apoptotic protease 4, CASP10
Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC. Isoform C is proteolytically inactive.
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基因ID
 - 843
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UniProt
 - Q92851
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途径
 - Apoptosis, Caspase Cascade in Apoptosis
 
抗原
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