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LAMP1 抗体 (Elab Fluor®700)

This anti-LAMP1 antibody is a 小鼠 单克隆 antibody detecting LAMP1 in FACS. Suitable for 人.
产品编号 ABIN7566893
发货至: 中国

Quick Overview for LAMP1 抗体 (Elab Fluor®700) (ABIN7566893)

抗原

See all LAMP1 抗体
LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This LAMP1 antibody is conjugated to Elab Fluor®700

应用范围

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Flow Cytometry (FACS)

克隆位点

H4A3
  • 原理

    Elab Fluor®700 Anti-Human CD107a/LAMP-1 Antibody[H4A3]

    亚型

    IgG
  • 应用备注

    Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.

    说明

    Matching Isotype Control: E-AB-F09792M1

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

    储存条件

    4 °C

    储存方法

    This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

    有效期

    12 months
  • 抗原

    LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

    别名

    CD107a/LAMP-1

    背景

    LAMP-1, LGP-120,Lysosome-Associated Membrane Protein 1,CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.

    基因ID

    3916

    UniProt

    P11279

    途径

    Autophagy
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