LAMP1 抗体 (Elab Fluor®700)
Quick Overview for LAMP1 抗体 (Elab Fluor®700) (ABIN7566893)
抗原
See all LAMP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Elab Fluor®700 Anti-Human CD107a/LAMP-1 Antibody[H4A3]
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亚型
- IgG
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应用备注
- Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.
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说明
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Matching Isotype Control: E-AB-F09792M1
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.
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储存条件
- 4 °C
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储存方法
- This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
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有效期
- 12 months
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- LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
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别名
- CD107a/LAMP-1
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背景
- LAMP-1, LGP-120,Lysosome-Associated Membrane Protein 1,CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.
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基因ID
- 3916
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UniProt
- P11279
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途径
- Autophagy
抗原
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