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PD-1 抗体 (Elab Fluor®700)

This anti-PD-1 antibody is a 大鼠 单克隆 antibody detecting PD-1 in FACS. Suitable for 小鼠.
产品编号 ABIN7566875
发货至: 中国

Quick Overview for PD-1 抗体 (Elab Fluor®700) (ABIN7566875)

抗原

See all PD-1 (PDCD1) 抗体
PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

适用

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小鼠

宿主

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大鼠

克隆类型

  • 198
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单克隆

标记

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This PD-1 antibody is conjugated to Elab Fluor®700

应用范围

  • 147
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Flow Cytometry (FACS)

克隆位点

29F-1A12
  • 原理

    Elab Fluor®700 Anti-Mouse CD279/PD-1 Antibody[29F.1A12]

    亚型

    IgG2a, kappa
  • 应用备注

    Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10 cells in 100 μL volume].

    说明

    Matching Isotype Control: E-AB-F09833M1

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

    储存条件

    4 °C

    储存方法

    This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

    有效期

    12 months
  • 抗原

    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

    别名

    CD279/PD-1

    背景

    Programmed Death-1,PD-1,CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.

    基因ID

    18566

    UniProt

    Q02242

    途径

    Cancer Immune Checkpoints
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