PD-1 抗体 (Elab Fluor®700)
Quick Overview for PD-1 抗体 (Elab Fluor®700) (ABIN7566875)
抗原
See all PD-1 (PDCD1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Elab Fluor®700 Anti-Mouse CD279/PD-1 Antibody[29F.1A12]
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亚型
- IgG2a, kappa
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应用备注
- Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10 cells in 100 μL volume].
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说明
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Matching Isotype Control: E-AB-F09833M1
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.
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储存条件
- 4 °C
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储存方法
- This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
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有效期
- 12 months
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- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
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别名
- CD279/PD-1
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背景
- Programmed Death-1,PD-1,CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.
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基因ID
- 18566
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UniProt
- Q02242
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途径
- Cancer Immune Checkpoints
抗原
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