CD8 抗体 (Elab Fluor®Violet 500)
Quick Overview for CD8 抗体 (Elab Fluor®Violet 500) (ABIN7566836)
抗原
See all CD8 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Elab Fluor®Violet 500 Anti-Human CD8a Antibody[OKT-8]
-
亚型
- IgG2a, kappa
-
-
-
-
应用备注
- Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.
-
说明
-
Matching Isotype Control: E-AB-F09802R
-
限制
- 仅限研究用
-
-
-
缓冲液
- Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.
-
储存条件
- 4 °C
-
储存方法
- This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
-
有效期
- 12 months
-
-
- CD8
-
别名
- CD8
-
背景
- CD8A,MAL,T-cell surface glycoprotein CD8 alpha chain,T-lymphocyte differentiation antigen T8/Leu-2,CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
-
基因ID
- 925
-
UniProt
- P01732
抗原
-