CD72 抗体 (FITC)
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- 抗原 See all CD72 抗体
- CD72 (CD72 Molecule (CD72))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD72 antibody is conjugated to FITC
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应用范围
- Flow Cytometry (FACS)
- 原理
- FITC Anti-Human CD72 Antibody[3F3]
- 克隆位点
- 3F3
- 亚型
- IgG2b, kappa
- Top Product
- Discover our top product CD72 Primary Antibody
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- 应用备注
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Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.
FCM: 5 µL/test - 说明
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Matching Isotype Control: (ABIN7469794)
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.
- 储存条件
- 4 °C
- 储存方法
- This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
- 有效期
- 12 months
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- 抗原
- CD72 (CD72 Molecule (CD72))
- 别名
- CD72 (CD72 产品)
- 背景
- Lyb-2,Ly-19.2,Ly-32.2,CD72 is a 39-43 kD type II membrane glycoprotein. It is a disulfide-linked homodimer belonging to C-type lectin family. CD72 is a pan-B cell marker expressed on pre-pre-B cells throughout B cell differentiation with the exception of plasma cells. It is also expressed on follicular dendritic cells, splenic red pulp macrophages (but not on peripheral blood monocytes), and liver Kupffer cells. CD72, a negative coreceptor of B cells, contains immunoreceptor tyrosine-based inhibitory motifs in the cytoplasmic domain which has been shown to recruit the tyrosine phosphatase SHP-1. Ligation of CD72 with its ligand regulates CD72 tyrosine dephosphorylation and SHP-1 dissociation to promote B cell activation and proliferation. CD100 and CD5 have been shown to be CD72 ligands. The CD100-CD72 interaction plays a role in maintenance of B cell homeostasis.
- 基因ID
- 971
- UniProt
- P21854
- 途径
- BCR Signaling
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