CD226 抗体 (APC)
Quick Overview for CD226 抗体 (APC) (ABIN7566522)
抗原
See all CD226 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- APC Anti-Human CD226/DNAM-1 Antibody[11A8]
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亚型
- IgG1, kappa
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应用备注
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Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.
FCM: 5 µL/test -
说明
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Matching Isotype Control: (ABIN7469762)
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.
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储存条件
- 4 °C
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储存方法
- This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
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有效期
- 12 months
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- CD226
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别名
- CD226,DNAM-1
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背景
- DNAM-1,PTA1,TLiSA1,DNAM-1 (CD226) is a ~65 kD glycoprotein expressed on cell surface of T cells, NK cells, monocytes/macrophages, platelets and megakaryocytes and a subset of B cells and a member of the immunoglobulin (Ig)-superfamily containing 2 Ig-like domains of the V-set. The ligands for CD226 are the poliovirus receptor (CD155) and its family member nectin-2 (CD112), which are broadly expressed on epithelial, endothelial and neuronal cells. CD226 is physically associated with LFA-1 in NK cells and activated T cells, and involved in LFA-1-mediated signaling.
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基因ID
- 10666
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UniProt
- Q15762
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
抗原
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