LTBR 抗体
Quick Overview for LTBR 抗体 (ABIN7566478)
抗原
See all LTBR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-LTβR (mouse), mAb (4H8 WH2) (preservative free)
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产品特性
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Monoclonal Antibody. Recognizes mouse LTbetaR. Isotype: Rat IgG2a. Clone: 4H8 WH2. Applications: FACS, FUNC (Blocking). Liquid. In PBS containing 10 % glycerol. The LTbetaR activates two different NF-kappaB pathways that lead to distinct patterns of gene induction, including selected chemokines and the cytokine BAFF, which is essential for the survival of mature B lymphocytes. LTbetaR activates the classical NF-kappaB (relA/p50) pathway, like the type 1 TNF receptor (TNFR1), that regulates proinflammatory genes, like the chemokine MIP1beta. However, LTbetaR, unlike TNFR1, also activates the processing of p100 to form RelB/p52 complexes, which activate genes involved in lymphoid organ formation and lymphocyte survival.
The LTbetaR activates two different NF-kappaB pathways that lead to distinct patterns of gene induction, including selected chemokines and the cytokine BAFF, which is essential for the survival of mature B lymphocytes. LTbetaR activates the classical NF-kappaB (relA/p50) pathway, like the type 1 TNF receptor (TNFR1), that regulates proinflammatory genes, like the chemokine MIP1beta. However, LTbetaR, unlike TNFR1, also activates the processing of p100 to form RelB/p52 complexes, which activate genes involved in lymphoid organ formation and lymphocyte survival.
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纯化方法
- Puified
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纯度
- >95 % (SDS-PAGE)
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免疫原
- Recombinant mouse LTbetaR (cysteine-rich region/aa 31-221).
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亚型
- IgG2a
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anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 66-215) antibody
LTBR 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 31-227) antibodyLTBR 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 1D1C5C8 unconjugated
anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 128-395) antibodyLTBR 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (N-Term) antibodyLTBR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 31-224) antibodyLTBR 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 31-227) antibodyLTBR 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 66-215) antibodyLTBR 适用: 人 WB 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 351-435) antibodyLTBR 适用: 人, 小鼠 WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (N-Term) antibodyLTBR 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- In PBS containing 10 % glycerol.
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储存液
- Without preservative
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注意事项
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
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+4°C
Stable for at least 1 year after receipt when stored at -20°C.
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- LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))
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别名
- LtbetaR
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UniProt
- P50284
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途径
- NF-kappaB Signaling
抗原
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