Recombinant CRP 抗体
Quick Overview for Recombinant CRP 抗体 (ABIN7566407)
抗原
See all CRP 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-CRP (human), mAb (rec.) (SH1177-F3)
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产品特性
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Recombinant Antibody. Recognizes human C-reactive protein (CRP). Applications: ELISA, WB. Clone: SH1177-F3. Isotype: Human IgG1. Formulation: Liquid. In PBS. C-reactive protein (CRP) is a major cyclic, pentameric acute phase protein compound consisting of five identical, noncovalently bound, nonglycosylated subunits. CRP is produced by the liver, and its plasma levels rise dramatically during inflammatory processes occurring in the body. CRP is an initiator of classical complement cascade, binds to several nuclear components (chromatin, histones, etc.), plays an important role in innate immunity and mediates activities associated with pre-immune nonspecific host resistance. Specifically, there is a 100-1000 fold increase of CRP in response to injury, infection or inflammation. CRP is opsonic, an initiator of the classical complement cascade, and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. CRP is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host, and initiates pathogen elimination by interacting with humoral and cellular effector systems in the blood. Patients with elevated basal levels of CRP have been shown to be an increased risk for hypertension and cardiovascular disease.
C-reactive protein (CRP) is a major cyclic, pentameric acute phase protein compound consisting of five identical, noncovalently bound, nonglycosylated subunits. CRP is produced by the liver, and its plasma levels rise dramatically during inflammatory processes occurring in the body. CRP is an initiator of classical complement cascade, binds to several nuclear components (chromatin, histones, etc.), plays an important role in innate immunity and mediates activities associated with pre-immune nonspecific host resistance. Specifically, there is a 100-1000 fold increase of CRP in response to injury, infection or inflammation. CRP is opsonic, an initiator of the classical complement cascade, and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. CRP is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host, and initiates pathogen elimination by interacting with humoral and cellular effector systems in the blood. Patients with elevated basal levels of CRP have been shown to be an increased risk for hypertension and cardiovascular disease.
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纯化方法
- Purified
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纯度
- >95 % (SDS-PAGE)
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免疫原
- Recombinant human C-reactive protein (CRP).
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亚型
- IgG1
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anti-C-Reactive Protein (CRP) (AA 17-224) antibody
CRP 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-C-Reactive Protein (CRP) (AA 20-222) antibodyCRP 适用: Pig WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-C-Reactive Protein (CRP) (AA 1-224) antibodyCRP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-C-Reactive Protein (CRP) (AA 14-224) antibodyCRP 适用: Cow WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-C-Reactive Protein (CRP) antibodyCRP 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1G1 unconjugated
anti-C-Reactive Protein (CRP) (AA 20-225) antibodyCRP 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-C-Reactive Protein (CRP) (Internal Region) antibodyCRP 适用: 人, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-C-Reactive Protein (CRP) (AA 125-224) antibodyCRP 适用: 人, 小鼠, 兔 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-C-Reactive Protein (CRP) antibodyCRP 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-C-Reactive Protein (CRP) (AA 20-230) antibodyCRP 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- In PBS.
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注意事项
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.Please handle under sterile conditions to avoid contamination.
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储存条件
- 4 °C,-20 °C
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储存方法
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Stable for at least 1 year after receipt when stored at -20°C.
Stable for at least 1 week when stored at +4°C.
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- CRP (C-Reactive Protein (CRP))
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别名
- CRP
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UniProt
- P02741
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途径
- Carbohydrate Homeostasis
抗原
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