CD31 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for CD31 抗体 (C-Term) (ABIN7565916)
抗原
See all CD31 (PECAM1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
原理
- CD31 Antibody
-
交叉反应 (详细)
- CD31 PECAM1 antibody is directed against rat CD31 protein.
-
产品特性
- Synonyms: rabbit anti-CD31 Antibody, rabbit anti-PECAM-1 antibody, Platelet endothelial cell adhesion molecule, PECAM-1, EndoCAM, GPIIA', PECA1, CD31 Antibody, PECAM1 Antibody, CD31/PECAM1 Antibody
-
纯化方法
- The product is delipidated and defibrinated antiserum.
-
过滤
- Sterile filtered
-
免疫原
-
Immunogen: This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the C-terminal domain of rat CD31 protein.
Immunogen Type: Conjugated Peptide
-
-
-
-
应用备注
- Application Note: CD31 antibody has been tested for use in ELISA, immunohistochemistry, and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 80 kDa in size corresponding to CD31 protein by western blotting in the appropriate stimulated tissue or cell lysate or extract. Immunohistochemistry Dilution: 4 μg/mL Western Blot Dilution: 1:500 ELISA Dilution: 1:20,000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 90 mg/mL
-
缓冲液
-
Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.
-
有效期
- 12 months
-
-
- CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
-
别名
- Pecam1
-
背景
- Background: Anti-CD31 antibody was designed, produced, and validated as part of the Joy Cappel Young Investigator Award (JCYIA). CD31 (PECAM-1) is a 130 kDa platelet endothelial cell adhesion molecule encoded by the PECAM1 gene found on chromosome 17 in humans. CD31 is expressed on platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. CD31 plays a key role in modulation of integrin-mediated cell adhesion, leukocyte transendothelial migration, angiogenesis, apoptosis and macrophage phagocytosis. CD31 is also expressed in certain tumors, including epithelioid hemangioendothelioma, epithelioid sarcoma-like hemangioendothelioma, other vascular tumors, histiocytic malignancies, and plasmacytomas. Anti-CD31 is ideal for researchers interested in Stem Cell Research, Epigenetics, and Cell-cycle Regulation research.
-
基因ID
- 29583
-
NCBI登录号
- NP_113779
-
UniProt
- Q3SWT0
-
途径
- Regulation of Actin Filament Polymerization
抗原
-