ABCB8 抗体
Quick Overview for ABCB8 抗体 (ABIN7565731)
抗原
See all ABCB8 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- ABCB8 Antibody
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产品特性
- Synonyms: Rabbit anti-ABCB8 antibody, ATP-binding cassette sub-family B member 8 mitochondrial, Mitochondrial ATP-binding cassette 1, M-ABC1, ABCB-8, ABCB
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纯化方法
- Anti-ABCB8 Antibody was prepared from monospecific, delipidated and defibrinated antiserum, with addition of sodium azide to 0.01 % .
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过滤
- Sterile filtered
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免疫原
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Immunogen: ABCB8 was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a internal portion of human ABCB8.
Immunogen Type: Conjugated Peptide
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anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 8 (ABCB8) (AA 469-718) antibody
ABCB8 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 8 (ABCB8) antibodyABCB8 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 8 (ABCB8) (AA 486-735) antibodyABCB8 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 8 (ABCB8) (AA 468-717) antibodyABCB8 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 8 (ABCB8) (AA 472-735) antibodyABCB8 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 8 (ABCB8) (AA 468-714) antibodyABCB8 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 8 (ABCB8) antibodyABCB8 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 8 (ABCB8) (C-Term) antibodyABCB8 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 8 (ABCB8) (AA 540-589) antibodyABCB8 适用: 人, 小鼠, Hamster WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Application Note: Anti-ABCB8 antibody has been tested by ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect band approximately 79.9 kDa in size corresponding to ABCB8 by western blotting in the appropriate cell lysate or extract. This antibody is suitable for use in ELISA. Western Blot Dilution: 1:250-1:500 ELISA Dilution: 1:20,000-1:50,000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 80 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.
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有效期
- 12 months
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- ABCB8 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 8 (ABCB8))
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别名
- ABCB8
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背景
- Background: This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI) (NCI) and is suitable for Cancer Research and drug resistance. ABCB8 is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI) (NCI). It has been found that ABC transporters are involved in mulitdrug resistance through their ability to control the presence of drugs in cells. Multidrug resistance is currently being looked at in particular reference to cancer that is resistant to treatment. ABCB8 seems to have particularly high resistance rates in renal cancer and cancer of the central nervous system. Another significant aspect of ABCB8 is that it is a mitochondrial transporter. There are very few ABC transporters localized to the mitochondria which implies information about them could be extremely important. ABCB8 may also be localized to other parts of the cell which are yet to be determined. Anti-ABCB8 antibody is ideal for researchers interested in Cancer Research and drug resistance.
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基因ID
- 11194
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NCBI登录号
- NP_009119
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UniProt
- Q9NUT2
抗原
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