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beta Actin 抗体 (AA 1-50)

Name: beta Actin 抗体 (AA 1-50)
SKU: ABIN724340
Availability: OutOfStock

This anti-beta Actin antibody is a 兔多克隆 antibody detecting beta Actin in WB, ELISA, IHC (p), FACS, IF (p) 和 IF (cc). Suitable for 人, 小鼠, 大鼠, 兔, Pig 和 Cow. This Primary Antibody has been cited in 272+ publications.

NLRP3 inflammasome activation was involved in P2Y14R deficiency. (beta Actin 抗体 (AA 1-50))

Rat lung lysate 30ug, probed (ABIN724340) at 1:200 overnight in 4 °C. (beta Actin 抗体 (AA 1-50))

SDS

Image kindly submitted by Piotr Mamczur from Wroclaw University. (beta Actin 抗体 (AA 1-50))

Human HeLa cell lysates probed with Rabbit Anti-beta Actin Polyclonal Antibody, Unconjugated . (beta Actin 抗体 (AA 1-50))

FACS

IF (cc)

Hepatic overexpression of HNF4α in rats decreased cholesterol levels in both plasma and liver. (beta Actin 抗体 (AA 1-50))

Expression pattern of hepatic cholesterol-regulatory genes under HNF4α overexpression in rat liver. (beta Actin 抗体 (AA 1-50))

HNF4α-upregulated SR-BI depends on PPARγ. (beta Actin 抗体 (AA 1-50))

High-temperature cultivation of an rhIL-10 expression strain impairs the maturation of G3-pro-rhIL10. (beta Actin 抗体 (AA 1-50))

High-temperature cultivation of an rhIL-10 expression strain impairs ER folding capacity. (beta Actin 抗体 (AA 1-50))

(a) Expression of viral N (Nucleoprotein) and G (Glycoprotein) genes mRNA in zebrafish embryonic fibroblast cell line (ZF4) with time after snakehead fish vesiculovirus (SHVV) infection. (beta Actin 抗体 (AA 1-50))

Expression of Mx and interferon (IFN) genes in ZF4 with time after SHVV infection. (beta Actin 抗体 (AA 1-50))

Expression of Retinoic acid-inducible gene I (RIG-I), Melanoma differentiation-associated gene 5 (MDA5), LGP2T, and LGP2a genes in ZF4 with time after SHVV infection. (beta Actin 抗体 (AA 1-50))

(a) The expression of DrLGP2a, DrLGP2b proteins during the infection with SHVV. (beta Actin 抗体 (AA 1-50))

Pro-Gly, but not Pro plus Gly (Pro+Gly), promoted the expression and secretion of IGF-1 in the HepG2 cells. (beta Actin 抗体 (AA 1-50))

Knockdown of PepT1 eliminated the increase of IGF-1 expression induced by Pro-Gly in the HepG2 cells. (beta Actin 抗体 (AA 1-50))

Pro-Gly activated JAK2/STAT5 signaling pathway in a PepT1-dependent manner. (beta Actin 抗体 (AA 1-50))

Inhibition of JAK2/STAT5 signaling pathway blocked the promotive effect of Pro-Gly on IGF-1 expression and secretion in the HepG2 cells. (beta Actin 抗体 (AA 1-50))

Acute or chronic injection of Pro-Gly, but not Pro plus Gly (Pro+Gly), stimulated IGF-1 expression and secretion in mice. (beta Actin 抗体 (AA 1-50))

Injection of JAK2/STAT5 inhibitor abolished the promotive effect of Pro-Gly on IGF-1 expression and secretion in mice. (beta Actin 抗体 (AA 1-50))

Protein expression of MTA1 by Western Blot analysis. (beta Actin 抗体 (AA 1-50))

Effects of stable YAP1 silencing in BGC-823 cells and stable YAP1 overexpressing in GES-1 cells on migration and invasion abilities in vitroThe wound healing assay was used to evaluate the migration properties of BGC-823 GC cells (A, G) and GES-1 cells (B, H). (beta Actin 抗体 (AA 1-50))

Effects of JQ1 treatment on cell proliferation, migration and invasion in ccRCC cell lines(A) Cell proliferation was determined by XTT assays (*P < 0. (beta Actin 抗体 (AA 1-50))

JQ1 treatment inhibited MYC expression in ccRCC cells(A) The expression level of MYC mRNA was significantly upregulated in ccRCC tissues compared with that in normal kidney tissues according to TCGA data (P < 0. (beta Actin 抗体 (AA 1-50))

Protein levels of NF-κB and NLRP3/Caspase-1 pathway in CIA rats. (beta Actin 抗体 (AA 1-50))

Clinical significance of BRD4 expression in ccRCC according to TCGA data(A) Overall survival (OS) was significantly shortened in patients with high BRD4 expression (top third) compared with that in patients with medium and low BRD4 expression (P = 0. (beta Actin 抗体 (AA 1-50))

The effect of LBP on the expression of GFAP, VEGF, and PEDF in the retinal tissue. (beta Actin 抗体 (AA 1-50))

Relative expression of AANAT, HIOMT, MT1, and MT2 in COCs of follicles of different sizes. (beta Actin 抗体 (AA 1-50))

Effect of E2 and ER antagonist ICI182780 on melatonin production and the expression of AANAT, HIOMT, MT1, and MT2 mRNA and protein in sheep COCs. (beta Actin 抗体 (AA 1-50))

Arginine inhibits HIF-1α to reduce LDHA expression after cerebral I/R injury. (beta Actin 抗体 (AA 1-50))

Upregulated cAMP suppressed acute gouty arthritis in vivo. (beta Actin 抗体 (AA 1-50))

Pyroptosis stress was invalidated once cAMP increased by Forskolin in vitro. (beta Actin 抗体 (AA 1-50))

Decreased cAMP exaggerated acute gouty arthritis in P2Y14R-KO rats. (beta Actin 抗体 (AA 1-50))

43 images

(272 references)

产品编号 ABIN724340

发货至: 中国

Quick Overview for beta Actin 抗体 (AA 1-50) (ABIN724340)

Key Features

High quality beta Actin Primary Antibody for the detection of ACTB.
Reliable product with high standard validation data

抗原

See all beta Actin (ACTB) 抗体

beta Actin (ACTB) (Actin, beta (ACTB))

适用

人, 小鼠, 大鼠, 兔, Pig, Cow

宿主

兔

克隆类型

多克隆

标记

This beta Actin antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

抗原表位
41

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15

15

8

7

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

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1
AA 1-50

交叉反应

Cow, 犬, 山羊, 人, 小鼠, Pig, 兔, 大鼠, 绵羊, Various Species

纯化方法

Purified by Protein A.

免疫原

MAP conjugated synthetic peptide derived from human beta Actin

亚型

IgG

Product Specific Information

What can the beta Actin Antibody ABIN724340 be used for?

This polyclonal beta Actin Antibody detects beta Actin. The beta Actin Antibody has been validated for various applications and can be used for the detection of beta Actin and derivatives by Western Blotting, ELISA, Immunohistochemistry (Paraffin-embedded Sections), Flow Cytometry, Immunofluorescence (Paraffin-embedded Sections), Immunofluorescence (Cultured Cells).

What validation data is available for this beta Actin Antibody?

The Primary Antibody is referenced in 256 publications and is characterized by a proven, very high reliability. It has currently 43 product images that show its performance in a variety of applications. beta Actin Antibody for the detection of beta Actin and derivatives.

What is the function of beta Actin?

This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. [provided by RefSeq, Jul 2008].
anti-Actin, beta (ACTB) (AA 2-16) antibody
ACTB 适用: 小鼠, 大鼠, 小鸡, 斑马鱼 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

anti-Actin, beta (ACTB) (AA 350-375) antibody
ACTB 适用: 人, 小鼠, Leopard Frog WB, ELISA, IF, FM 宿主: 兔 Polyclonal unconjugated

anti-Actin, beta (ACTB) (AA 1-25) antibody
ACTB 适用: 人, 小鼠, 大鼠, Pig, Cow WB, IHC (p) 宿主: 小鼠 Monoclonal 1A2 unconjugated

anti-Actin, beta (ACTB) (AA 1-375) antibody
ACTB 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3G4-F9 unconjugated

anti-Actin, beta (ACTB) (N-Term) antibody
KO Validated ACTB 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Actin, beta (ACTB) antibody
ACTB 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), FACS, DNA Mic 宿主: 小鼠 Monoclonal 137CT26-1-1 unconjugated

anti-Actin, beta (ACTB) antibody
ACTB 适用: 人, 小鼠, 小鸡, 兔, Pig, Cow, Hamster, 山羊, 鱼 WB, ELISA 宿主: 小鼠 Monoclonal 2D1D10 unconjugated

anti-Actin, beta (ACTB) (AA 1-50) antibody
ACTB 适用: 人 WB, ELISA, IHC, IF, IP, FACS 宿主: 小鼠 Monoclonal 1D12E12B5 unconjugated

anti-Actin, beta (ACTB) (N-Term) antibody
ACTB 适用: 人, 小鼠, 大鼠, 小鸡, 兔, 犬, 猴, Pig, Cow, 绵羊, Hamster, 马, 豚鼠, 山羊, Cat, Avian, 驴 WB, IF 宿主: 山羊 Polyclonal unconjugated

anti-Actin, beta (ACTB) (Middle Region) antibody
ACTB 适用: 人, 小鼠, 大鼠, Pig, Cow, 绵羊, 斑马鱼, 马, 山羊 WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:5000-50000
IHC/IF 1:200-1000
ICC 1:100-500
FACS 1μg/Test

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C for 12 months.

有效期

12 months
Manescu, Catalin, Baldea, Mateescu, Rosu, Boboc, Istrate-Ofiteru, Liliac, Streba, Kumar-Singh, Pirici: "Aquaporin 4 modulation drives amyloid burden and cognitive abilities in an APPPS1 mouse model of Alzheimer's disease." in: Alzheimer's & dementia : the journal of the Alzheimer's Association, Vol. 21, Issue 5, pp. e70164, (2025) (PubMed).

Bâldea, Soran, Stegarescu, Opriș, Kacso, Tripon, Adascalitei, Fericel, Decea, Lung: "Lilium candidum Extract Loaded in Alginate Hydrogel Beads for Chronic Wound Healing." in: Gels (Basel, Switzerland), Vol. 11, Issue 1, (2025) (PubMed).

Chen, Pan, Tang, Cheng, Zhao, Zhang, Liao, Liu, Zhuang, Zhang, Chen, Lei, Li, Li, Wang, Wan: "Arginine is neuroprotective through suppressing HIF-1α/LDHA-mediated inflammatory response after cerebral ischemia/reperfusion injury." in: Molecular brain, Vol. 13, Issue 1, pp. 63, (2021) (PubMed).

Li, Jiang, Ye, Zhou, Liu, Yang, Hao, Hu: "P2Y14 receptor has a critical role in acute gouty arthritis by regulating pyroptosis of macrophages." in: Cell death & disease, Vol. 11, Issue 5, pp. 394, (2021) (PubMed).

Yang, Tang, Wang, Zhang, Zan: "Melatonin promotes triacylglycerol accumulation via MT2 receptor during differentiation in bovine intramuscular preadipocytes." in: Scientific reports, Vol. 7, Issue 1, pp. 15080, (2019) (PubMed).

Huang, Zhu, Yi, Yan, Wei, Yang, Chen, Huang: "A novel TRAIL mutant-TRAIL-Mu3 enhances the antitumor effects by the increased affinity and the up-expression of DR5 in pancreatic cancer." in: Cancer chemotherapy and pharmacology, Vol. 82, Issue 5, pp. 829-838, (2019) (PubMed).

Lai, Jiang, Xie, Liu, Tang, Xiao, Gao, Jia, Bai: "Intestinal Pathology and Gut Microbiota Alterations in a Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) Mouse Model of Parkinson's Disease." in: Neurochemical research, Vol. 43, Issue 10, pp. 1986-1999, (2019) (PubMed).

Li, Feng, Hu, Chen, Sha, Zhang, Fan: "Effect of melatonin on attenuating the isoflurane-induced oxidative damage is related to PKCα/Nrf2 signaling pathway in developing rats." in: Brain research bulletin, Vol. 143, pp. 9-18, (2019) (PubMed).

Jia, Kong, Guo, Li, Quan: "Enhanced antitumor effect of combination of annexin A1 knockdown and bortezomib treatment in multiple myeloma in vitro and in vivo." in: Biochemical and biophysical research communications, Vol. 505, Issue 3, pp. 720-725, (2019) (PubMed).

Zhang, Li, Fu, Lin, Lin, Tu: "MiR-214 inhibits snakehead vesiculovirus (SHVV) replication by targeting host GS." in: Fish & shellfish immunology, Vol. 84, pp. 299-303, (2019) (PubMed).

Song, Ma, Hua, Xu, Li, Ju, Hou: "Functional role of RRS1 in breast cancer cell proliferation." in: Journal of cellular and molecular medicine, Vol. 22, Issue 12, pp. 6304-6313, (2019) (PubMed).

Feng, Su, Lin, Tu: "Development of a reverse genetics system for snakehead vesiculovirus (SHVV)." in: Virology, Vol. 526, pp. 32-37, (2019) (PubMed).

Cui, Xing, Huang, Li, Lu, Wang, Wang, Huang, Cheng, Hao, Peng, Liu, Dai, Yuan: "Signaling pathways involved in the expression of SZNF and the target genes binding with SZNF related to cyadox." in: Biomedicine & pharmacotherapy, Vol. 108, pp. 1879-1893, (2019) (PubMed).

Voogdt, Merchant, Wagenaar, van Putten: "Evolutionary Regression and Species-Specific Codon Usage of TLR15." in: Frontiers in immunology, Vol. 9, pp. 2626, (2019) (PubMed).

Zhang, Do, Chandimali, Lee, Mok, Kim, Kim, Kwon, Jeong: "Non-thermal plasma treatment improves chicken sperm motility via the regulation of demethylation levels." in: Scientific reports, Vol. 8, Issue 1, pp. 7576, (2019) (PubMed).

Pang, Wang, Ran, Lin, Wang, Guan, Yuan, Fang, Liu, Wang et al.: "Inhibitory Effect of Methotrexate on Rheumatoid Arthritis Inflammation and Comprehensive Metabolomics Analysis Using Ultra-Performance Liquid Chromatography-Quadrupole Time of Flight-Mass ..." in: International journal of molecular sciences, Vol. 19, Issue 10, (2019) (PubMed).

Zhang, Zhao, Li, Li: "Neuroprotective effects of matrix metalloproteinases in cerebral ischemic rats by promoting activation and migration of astrocytes and microglia." in: Brain research bulletin, Vol. 146, pp. 136-142, (2019) (PubMed).

Xia, Qu, Jia, He, Li, Zhao, Mao, Zhao: "Overexpression of Forkhead box C1 attenuates oxidative stress, inflammation and apoptosis in chronic obstructive pulmonary disease." in: Life sciences, Vol. 216, pp. 75-84, (2019) (PubMed).

Su, Tian, Liu, Ci, Lv: "Purinergic P2X7 receptor blockade mitigates alcohol-induced steatohepatitis and intestinal injury by regulating MEK1/2-ERK1/2 signaling and egr-1 activity." in: International immunopharmacology, Vol. 66, pp. 52-61, (2019) (PubMed).

Xiao, Hu, Song, Zhang, Dong, Jiang, Zhang, Yuan, Zhao: "Profile of melatonin and its receptors and synthesizing enzymes in cumulus-oocyte complexes of the developing sheep antral follicle-a potential estradiol-mediated mechanism." in: Reproductive biology and endocrinology : RB&E, Vol. 17, Issue 1, pp. 1, (2019) (PubMed).

show more references
抗原

beta Actin (ACTB) (Actin, beta (ACTB))

别名

beta Actin

背景

Synonyms: BRWS1, PS1TP5BP1, Actin, cytoplasmic 1, Beta-actin, ACTB
Background: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

基因ID

60

UniProt

P60709

途径

Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Maintenance of Protein Location, Phototransduction