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Recombinant OCT4 抗体

This anti-OCT4 antibody is a 兔 Chimeric antibody detecting OCT4 in WB 和 IHC. Suitable for 人.
产品编号 ABIN7543401
发货至: 中国

Quick Overview for Recombinant OCT4 抗体 (ABIN7543401)

抗原

See all OCT4 (POU5F1) 抗体
OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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Chimeric

标记

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This OCT4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

41B1
  • 原理

    Anti-Oct3/4 [41B1], Rabbit IgG, kappa

    特异性

    The original antibody is specific for OCT3/4. OCT3/4 is a transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). It forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. It is critical for early embryogenesis and for embryonic stem cell pluripotency.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG2b

    纯化方法

    Protein A affinity purified

    免疫原

    The original antibody was generated by immunizing mice with recombinant protein OCT3/4.

    亚型

    IgG kappa
  • 应用备注

    The antibody 41B1 and the commercial antibody C-10 were used to stain collagen tumor, dysgerminoma and testicular tissue in immunohistochemistry. Results showed the antibody specificity is comparable to the commercial antibody. Further, the staining intensity of the antibody 41B1 was higher than the commercial antibody (CN113072642A).

    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format for improved compatibility with existing reagents assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

    别名

    Oct3/4

    背景

    C-10, KS20.8, POU5F1, Oct4, POU domain, class 5, transcription factor 1, POU domain, class 5, transcription factor 1, Octamer-binding protein 3, Oct-3, Octamer-binding protein 4, Oct-4, Octamer-binding transcription factor 3, OTF-3, CGMCC NO 20779

    UniProt

    Q01860

    途径

    Stem Cell Maintenance
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