Recombinant Estrogen Receptor alpha 抗体
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Quick Overview for Recombinant Estrogen Receptor alpha 抗体 (ABIN7543366)
抗原
See all Estrogen Receptor alpha (ESR1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Estrogen receptor [4E11], Mouse IgG2b, kappa
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特异性
- The antibody is specific for estrogen receptor ER-α36. The estrogen receptor ER-α36 is an estrogen receptor subtype mainly expressed on the cell membrane, it mediates the non-genomic estrogen signal pathway, and can inhibit the traditional estrogen signal pathway. It plays a vital role in the occurrence and development of diseases. For example its expression level is closely related to some biological indicators of cancer.
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG2b
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纯化方法
- Protein A affinity purified
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免疫原
- The original antibody was generated by immunizing mice with estrogen receptor ER-alpha36.
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亚型
- IgG2b kappa
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应用备注
- The antibody specifically recognized ER-α36 protein expressed by SUM159 cells, as confirmed by ELISA analysis (CN107987164).
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
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别名
- Estrogen receptor
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背景
- ER, ERα36, ER-α36, hER-α36, ESR1, ER-alpha, NR3A1, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1, ER-alpha Estradiol receptor, Nuclear receptor subfamily 3 group A member 1
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UniProt
- P03372
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途径
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
抗原
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