Recombinant KRT20 抗体 (AA 411-424)
Quick Overview for Recombinant KRT20 抗体 (AA 411-424) (ABIN7543324)
抗原
See all KRT20 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 411-424
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原理
- Anti-Cytokeratin 20 [10F6B12A9], Rabbit IgG, kappa
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特异性
- This antibody is specific for amino acids 411-424 of human cytokeratin 20. Cytokeratins are intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. There are 19 keratin polypeptides are found in human epithelium. Cytokeratin 20 plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, it plays a role in the secretion of mucin in the small intestine.
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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纯化方法
- Protein A affinity purified
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免疫原
- The original antibody was generated by immunizing female ICR mice with human CK20 peptide (amino acids 411-424) conjugated to KLH in equal volume of Freund's incomplete adjuvant.
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亚型
- IgG kappa
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应用备注
- This antibody can bind human cytokeratin 20 in an ELISA. It is also capable of detecting human cytokeratin 20 in a western blot assay. This antibody is similar to commercially available anti-Cytokeratin 20 antibody KS20.8 in staining various human tissues. This antibody was used in the immunohistochemical staining of paraffin sections of stomach, colon and colonic cancer tissues (CN109734805).
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- KRT20 (Keratin 20 (KRT20))
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别名
- Cytokeratin 20
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背景
- CK20, CK-20, K20, KRT20, Cytokeratin-20, Keratin-20, Keratin type I cytoskeletal 20 ,Protein IT, CGMCC No 16204, Ks20.8
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UniProt
- P35900
抗原
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