Recombinant CD7 抗体
Quick Overview for Recombinant CD7 抗体 (ABIN7543249)
抗原
See all CD7 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Anti-CD7 [3A1f], Mouse IgG1, kappa
-
特异性
- This antibody binds human CD7. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. CD7 is useful in the identification of precursor T cells as well as an important marker for the identification of leukemic T cells.
-
产品特性
-
Original Species of Ab: Mouse
Original Format of Ab: IgG1
-
纯化方法
- Protein A affinity purified
-
亚型
- IgG1 kappa
-
-
anti-CD7 (CD7) (AA 26-134) antibody
CD7 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD7 (CD7) (AA 23-128) antibodyCD7 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD7 (CD7) (AA 26-180) antibodyCD7 适用: 人 FACS, ELISA, IHC 宿主: 小鼠 Monoclonal 3D11F12 unconjugated
anti-CD7 (CD7) antibodyCD7 适用: 人 FACS, WB, IP, IHC (p) 宿主: 小鼠 Monoclonal MEM-186 unconjugated
anti-CD7 (CD7) antibodyCD7 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-CD7 (CD7) (AA 26-180) antibodyCD7 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2B1C9 unconjugated
anti-CD7 (CD7) (AA 72-175) antibodyCD7 适用: 人 FACS, ELISA, IHC 宿主: 小鼠 Monoclonal 5B10E3 unconjugated
anti-CD7 (CD7) (AA 24-150) antibodyCD7 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD7 (CD7) (AA 21-240) antibodyCD7 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1B8 unconjugated
anti-CD7 (CD7) antibodyCD7 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-007R unconjugated Recombinant Antibody
-
-
应用备注
- The binding affinity of the scFv version of this antibody was determined using surface plasmon resonance. The affinity of the scFv antibody for human CD7 was found to be 1.8 nM. This the scFv version of this antibody was also used in the generation of single-chain Fv (scFv) immunotoxins specific for the T cell-associated antigen CD7 as a novel therapeutic agent for treatment of human T cell malignancies (PMID: 9120282). This antibody was also used in the generation of a therapeutic fusion protein scFvCD7:sTRAIL, designed to induce target antigen-restricted apoptosis in human T-cell tumors. The binding of the fusion protein to CD7 was tested with flow cytometry (PMID: 15833872).
-
限制
- 仅限研究用
-
-
-
浓度
- 1 mg/mL
-
缓冲液
- PBS with 0.02 % Proclin 300.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
-
-
- CD7
-
别名
- CD7
-
背景
- GP40, TP41, T-cell antigen CD7, T-cell leukemia antigen, T-cell surface antigen Leu-9, 3aIf
-
UniProt
- P09564
-
途径
- Cell-Cell Junction Organization
抗原
-
