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Recombinant CEACAM8 抗体

This anti-CEACAM8 antibody is a 小鼠 单克隆 antibody detecting CEACAM8 in FACS, IF, ISG 和 ISt. Suitable for 人.
产品编号 ABIN7543166
发货至: 中国

Quick Overview for Recombinant CEACAM8 抗体 (ABIN7543166)

抗原

See all CEACAM8 抗体
CEACAM8 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 (CEACAM8))

抗体类型

Recombinant Antibody

适用

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宿主

  • 54
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小鼠

克隆类型

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  • 1
单克隆

标记

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This CEACAM8 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Immunoscintigraphy (ISG), Immunostaining (ISt)

克隆位点

BW 250-183
  • 原理

    Anti-CD66b [BW 250/183], Mouse IgG1, kappa

    特异性

    This antibody binds the human CD66b, which is expressed on the surface of granulocytes.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    纯化方法

    Protein A affinity purified

    免疫原

    The original antibody was generated by immunizing mice with CEA positive adenocarcinoma cells preferably from lungs.

    亚型

    IgG1 kappa
  • 应用备注

    This murine antibody reacted with granulocytes, colon mucosa and faintly with pancreatic ducts (PMID: 2410375). The radioactive isotope technetium-99m labelled version of this antibody is also called Besilesomab (trade name Scintimun). It has been studied widely for therapeutic applications. Technetium-99m-Labeled BW 250/183 was used to study the inflamatory process and identification of the inflamatory foci using immunoscintigraphy (PMID: 2157831, 1565572). This antibody is also used for scintiographic imaging of soft tissue infections, peripheral bone, and abdominal infections (PMID: 8023170). Tc-99m-labeled antibody has also been used in the localization of extramedullary hematopoiesis (PMID: 11953571). Rhenium-188-labelled BW250/183 was developed for adjuvant conditioning radioimmunotherapy of bone marrow before bone marrow transplantation. Immunoreactivity of the reduced and rhenium-incorporated antibody was determined by indirect immunofluorescence, by means of a whole blood staining method follwoed by flow ctometric analysis (PMID: 10541824). 90Y-label is reportedled antibody is reported to be used in the study of expression of CD66b in non-Hodgkin lymphomas and multiple myeloma usinf flow cytometry (PMID: 20887387).

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    CEACAM8 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 (CEACAM8))

    别名

    CD66b

    背景

    CEACAM8, CGM6, Carcinoembryonic antigen-related cell adhesion molecule 8, Carcinoembryonic antigen CGM6, CD67 antigen, Non-specific cross-reacting antigen, NCA-95

    UniProt

    P31997
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