Recombinant N-Cadherin 抗体 (Extracellular Domain)
Quick Overview for Recombinant N-Cadherin 抗体 (Extracellular Domain) (ABIN7543136)
抗原
See all N-Cadherin (CDH2) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Extracellular Domain
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原理
- Anti-N-cadherin [8C11], Rabbit IgG, kappa
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特异性
- This antibody recognizes human, rabbit and hamster extracellular domain of N-cadherin. It does not cross react with this protein in mouse, rat cow and pig. N-cadherin is a calcium-dependent cell adhesion protein.
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交叉反应
- Hamster, 兔
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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纯化方法
- Protein A affinity purified
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免疫原
- This antibody was raised by immunizing mice with an extracellular domain of the recombinant human N-cadherin.
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亚型
- IgG kappa
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anti-Cadherin 2 (CDH2) (AA 701-800) antibody
CDH2 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 2 (CDH2) antibodyCDH2 适用: 人, 小鼠, 犬, 猴 WB, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 2G7 unconjugated
anti-Cadherin 2 (CDH2) (AA 750-850) antibodyCDH2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 2 (CDH2) antibodyCDH2 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 5D5 unconjugated
anti-Cadherin 2 (CDH2) (AA 45-238) antibodyCDH2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 2 (CDH2) (AA 685-784) antibodyCDH2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 2 (CDH2) (AA 295-414) antibodyCDH2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 2 (CDH2) (Extracellular Domain) antibodyCDH2 适用: 人 WB, IHC, IF, FACS, IHC (f) 宿主: 小鼠 Monoclonal 8C11 unconjugated
anti-Cadherin 2 (CDH2) antibodyCDH2 适用: 人 WB, IHC, IHC (f) 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
anti-Cadherin 2 (CDH2) (AA 701-714), (Middle Region) antibodyCDH2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- 8C11 antibody inhibits cells' motility, as it blocks extracellular domain of N-cadherin which is responsible for this function (Kim et al., 2000). This antibody has also been widely used in the detection and analysis of N-cadherin. For instance, it was utilized to identify this protein in A549 cells via immunofluorescence (Shintani et al., 2011). Another group used successfully 8C11 to analyze the levels of N-cadherin expression via Western blot (Chen et al., 2015). Finally, this antibody was used to label N-cadherin in tumor tissues of a metastasis model via immunohistochemistry (Li et al., 2019).
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- N-Cadherin (CDH2) (Cadherin 2 (CDH2))
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别名
- N-cadherin
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背景
- CD325, Cadherin-2, CDw325, Neural cadherin, n-cadherin, ncadherin
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UniProt
- P19022
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途径
- Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane
抗原
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