电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Recombinant N-Cadherin 抗体 (Extracellular Domain)

The 小鼠 单克隆 anti-N-Cadherin antibody (Clone 8C11) (ABIN7543135) specifically detects N-Cadherin in WB, IHC, IF 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7543135
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant N-Cadherin 抗体 (Extracellular Domain) (ABIN7543135)

抗原

See all N-Cadherin (CDH2) 抗体
N-Cadherin (CDH2) (Cadherin 2 (CDH2))

抗体类型

Recombinant Antibody

适用

  • 174
  • 113
  • 79
  • 21
  • 18
  • 14
  • 9
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 114
  • 72
  • 4
  • 2
  • 2
  • 1
小鼠

克隆类型

  • 98
  • 96
  • 1
单克隆

标记

  • 87
  • 19
  • 8
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This N-Cadherin antibody is un-conjugated

应用范围

  • 125
  • 70
  • 43
  • 43
  • 32
  • 28
  • 17
  • 16
  • 14
  • 13
  • 9
  • 9
  • 4
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

8C11
  • 抗原表位

    • 19
    • 16
    • 15
    • 8
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Extracellular Domain

    原理

    Anti-N-cadherin [8C11], Mouse IgG1, kappa

    特异性

    This antibody recognizes human, rabbit and hamster extracellular domain of N-cadherin. It does not cross react with this protein in mouse, rat cow and pig. N-cadherin is a calcium-dependent cell adhesion protein.

    交叉反应

    Hamster, 兔

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    纯化方法

    Protein A affinity purified

    免疫原

    This antibody was raised by immunizing mice with an extracellular domain of the recombinant human N-cadherin.

    亚型

    IgG1 kappa
  • 应用备注

    8C11 antibody inhibits cells' motility, as it blocks extracellular domain of N-cadherin which is responsible for this function (Kim et al., 2000). This antibody has also been widely used in the detection and analysis of N-cadherin. For instance, it was utilized to identify this protein in A549 cells via immunofluorescence (Shintani et al., 2011). Another group used successfully 8C11 to analyze the levels of N-cadherin expression via Western blot (Chen et al., 2015). Finally, this antibody was used to label N-cadherin in tumor tissues of a metastasis model via immunohistochemistry (Li et al., 2019).

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    N-Cadherin (CDH2) (Cadherin 2 (CDH2))

    别名

    N-cadherin

    背景

    CD325, Cadherin-2, CDw325, Neural cadherin, n-cadherin, ncadherin

    UniProt

    P19022

    途径

    Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane
You are here: