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Recombinant ICOS 抗体

This anti-ICOS antibody is a 兔 Chimeric antibody detecting ICOS in FACS 和 BR. Suitable for 小鼠.
产品编号 ABIN7543074
发货至: 中国

Quick Overview for Recombinant ICOS 抗体 (ABIN7543074)

抗原

See all ICOS 抗体
ICOS (Inducible T-Cell Co-Stimulator (ICOS))

抗体类型

Recombinant Antibody

适用

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小鼠

宿主

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  • 1
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克隆类型

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Chimeric

标记

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This ICOS antibody is un-conjugated

应用范围

  • 72
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Flow Cytometry (FACS), Blocking Reagent (BR)

克隆位点

7E-17G9
  • 原理

    Anti-ICOS [7E.17G9], Rabbit IgG, kappa

    特异性

    This anitbody binds to mouse ICOS (CD278).

    产品特性

    Original Species of Ab: Rat

    Original Format of Ab: IgG2b

    纯化方法

    Protein A affinity purified

    免疫原

    Rats were immunized i.m. three times with 500 mg murine ICOS cDNA in the pAXEF mammalian expression vector and boosted twice with 200 mg murine ICOS hexahistidine fusion protein.

    亚型

    IgG kappa
  • 应用备注

    This antibody can be used to detect mouse ICOS by flow-cytometry. Maazi et al (2015, PMID: 25769613) showed that 7E.17G9 can inhibit ICOS interaction with its ligand ICOSL.

    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2b format, for improved compatibility with existing reagents, assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    ICOS (Inducible T-Cell Co-Stimulator (ICOS))

    别名

    ICOS

    背景

    CD278, AILIM, CVID1, inducible T-cell co-stimulator, inducible T-cell costimulator, 7E.17G9.G1.G7

    途径

    Cancer Immune Checkpoints
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