Recombinant TNFSF4 抗体
Quick Overview for Recombinant TNFSF4 抗体 (ABIN7543010)
抗原
See all TNFSF4 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-OX40L [OX-89], Rabbit IgG, kappa
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特异性
- This antibody is specific for murine CD252 (the ligand for OX40), expression of which is restricted to activated B cells, dendritic cells, microglia and endothelial cells.
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产品特性
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Original Species of Ab: Rat
Original Format of Ab: IgG1
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纯化方法
- Protein A affinity purified
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免疫原
- This antibody was prepared by immunizing PVG rats with a recombinant chimeric protein consisting of domains 3 and 4 of rat CD4 and the extracellular region of mouse CD134L.
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亚型
- IgG kappa
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anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4) (AA 51-183) antibody
TNFSF4 适用: 人 FACS, ELISA 宿主: 兔 Monoclonal DM112 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4) (AA 141-199) antibodyTNFSF4 适用: 小鼠, 大鼠 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4) (AA 1-183) antibodyTNFSF4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4) (AA 111-160) antibodyTNFSF4 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4) (AA 49-198) antibodyTNFSF4 适用: 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4) (AA 97-125) antibodyTNFSF4 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB30006 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4) (AA 98-126), (Middle Region) antibodyTNFSF4 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- This antibody binds mouse CD134L, and has been shown to bind activated B cells and DCs, as well as CD134L-transfected fibroblast cells, though not activated T cells, in labelling and immunohistochemical analysis (Malmstro m, 2001). In addition, this antibody is able to partially block the interaction between CD134 and CD134L. This blocking effect could be responsible for the ability of this antibody to prevent T cell accumulation in the intestine of T cell-restored SCID mice and inhibits the development of Th1-mediated colitis.
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))
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别名
- OX40L
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背景
- CD252, Tumor necrosis factor ligand superfamily member 4, OX40 ligand, CD134 ligand, OX40R
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UniProt
- P43488
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途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation, Cancer Immune Checkpoints
抗原
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