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HEY1 抗体 (Internal Region)

This anti-HEY1 antibody is a 兔 多克隆 antibody detecting HEY1 in WB, ELISA 和 IHC. Suitable for 人.
Rockland
产品编号 ABIN7540592
Supplier Product No.: 600-401-hb5s
发货至: 中国

Quick Overview for HEY1 抗体 (Internal Region) (ABIN7540592)

抗原

See all HEY1 抗体
HEY1 (Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1))

适用

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宿主

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克隆类型

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多克隆

标记

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This HEY1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
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    Internal Region

    Supplier Product No.

    600-401-hb5s

    Supplier

    Rockland

    原理

    HEY1 Antibody

    交叉反应 (详细)

    This affinity purified antibody is directed against human HEY1.

    纯化方法

    The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.

    过滤

    Sterile filtered

    免疫原

    Anti-HEY1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal portion of human HEY1 conjugated to Keyhole Limpet Hemocyanin (KLH).

    亚型

    IgG
  • 应用备注

    ELISA_Dilution: 1:10,000 - 1:50,000

    Immunohistochemistry_Dilution: 1:100

    Western_Blot_Dilution: 1:1000

    说明

    Anti-HEY1 Antibody has been tested in Western Blot, ELISA, and Immunohistochemistry. Expect a band at ~33 kDa in western blot using appropriate tissues or lysates.  Positive control used is a recombinant human Hey1 at 1μg/mL for WB, human cerebellum tissue at 1:100 for IHC.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.

    有效期

    12 months
  • 抗原

    HEY1 (Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1))

    别名

    HEY1

    背景

    Rabbit Anti-HEY1 Antibody, BHLHB31, CHF2, HERP2, HESR1, HRT1, Hairy/Enhancer-Of-Split Related With YRPW Motif 1, Hes Related Family BHLH Transcription Factor With YRPW Motif 1, Hairy And Enhancer Of Split-Related Protein 1, Class B Basic Helix-Loop-Helix Protein 31, Cardiovascular Helix-Loop-Helix Factor 2, Hairy-Related Transcription Factor 1, HES-Related Repressor Protein 1, HRT-1, HESR-1, CHF-2, OAF1,HEY1 belongs to the hairy and enhancer of split-related family (HESR), a transcriptional repressor family.  This nuclear protein is induced by the Notch pathway and is mainly associated with cardiovascular development. This family is known to repress GATA4, GATA6, MASH1, and NEUROD4 downstream effects. It's role in liver cancer cell self-renewal is still being studied, as it's suspected role in neurogenesis in mice. Hey1 is associated with diseases such as mesenchymal and periosteal chondrosarcoma. Anti-HEY1 antibody is useful for researchers interested in cancer research, neuroscience research, and Notch signalling.

    基因ID

    23462

    NCBI登录号

    NP_001035798

    UniProt

    Q9Y5J3

    途径

    Tube Formation
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