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HEY1 抗体 (Internal Region)

HEY1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6262226
发货至: 中国
  • 抗原 See all HEY1 抗体
    HEY1 (Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1))
    抗原表位
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 26
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 18
    • 7
    • 1
    克隆类型
    • 20
    • 6
    多克隆
    标记
    • 22
    • 2
    • 1
    • 1
    This HEY1 antibody is un-conjugated
    应用范围
    • 20
    • 13
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    HEY1 Antibody detects endogenous levels of total HEY1.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human HEY1, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product HEY1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    HEY1 (Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1))
    别名
    HEY1 (HEY1 产品)
    别名
    BHLHb31 antibody, CHF2 antibody, HERP2 antibody, HESR1 antibody, HRT-1 antibody, OAF1 antibody, AI316788 antibody, AI414254 antibody, HRT1 antibody, Herp2 antibody, Hesr1 antibody, bHLHb31 antibody, hesr-1 antibody, id:ibd1292 antibody, zgc:110572 antibody, bc8 antibody, chf2 antibody, herp2 antibody, hesr1 antibody, hrt1 antibody, oaf1 antibody, xbc8 antibody, hes related family bHLH transcription factor with YRPW motif 1 antibody, hairy/enhancer-of-split related with YRPW motif 1 antibody, hes-related family bHLH transcription factor with YRPW motif 1 antibody, hes related family bHLH transcription factor with YRPW motif 1 S homeolog antibody, HEY1 antibody, Hey1 antibody, hey1 antibody, hey1.S antibody
    背景

    Description: Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3' (PubMed:11095750). Downstream effector of Notch signaling required for cardiovascular development. Specifically required for the Notch-induced endocardial epithelial to mesenchymal transition, which is itself criticial for cardiac valve and septum development. May be required in conjunction with HEY2 to specify arterial cell fate or identity. Promotes maintenance of neuronal precursor cells and glial versus neuronal fate specification. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6 and by the neuronal bHLH factors ASCL1/MASH1 and NEUROD4/MATH3 (PubMed:15485867). Involved in the regulation of liver cancer cells self-renewal (PubMed:25985737).

    Gene: HEY1

    分子量
    32-34 kDa
    基因ID
    23462
    UniProt
    Q9Y5J3
    途径
    Tube Formation
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