GRIN1/NMDAR1 抗体
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北京 101111
Quick Overview for GRIN1/NMDAR1 抗体 (ABIN7540585)
抗原
See all GRIN1/NMDAR1 (GRIN1) 抗体适用
宿主
克隆类型
标记
应用范围
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Supplier Product No.
- 600-401-d85
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Supplier
- Rockland
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原理
- NMDA R1, Splice Variant C1 Antibody
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交叉反应 （详细）
- Anti-NMDA R1, Splice Variant C1 antibody is directed against NMDA R1 receptor protein.
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纯化方法
- The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.
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免疫原
- Anti-NMDA R1, Splice Variant C1 Antibody was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues specific to the NR1 subunit, C1 splice variant insert.
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亚型
- IgG
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anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) (AA 600-700) antibody
GRIN1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) (Internal Region) antibodyVerified GRIN1 适用: 人, 小鼠 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) (C-Term) antibodyGRIN1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) (pSer890) antibodyGRIN1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) (AA 42-361) antibodyGRIN1 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S308-48 unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) (AA 42-361) antibody (HRP)GRIN1 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S308-48 HRP
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) (AA 42-361) antibody (FITC)GRIN1 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S308-48 FITC
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) (AA 42-361) antibody (Biotin)GRIN1 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S308-48 Biotin
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) (AA 42-361) antibody (PE)GRIN1 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S308-48 PE
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) (AA 42-361) antibody (APC)GRIN1 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S308-48 APC
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应用备注
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Immunohistochemistry_Dilution: 1:1000-2000
Western_Blot_Dilution: 1:1000
Other: User Optimized
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说明
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Anti-NMDA R1, Splice Variant C1 (Rabbit) Antibody is tested for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 120 kDa in size corresponding to the NR1 subunit of the NMDA receptor containing the C1 splice variant insert in the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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Reconstitution_Buffer: Neutral PBS
Reconstitution_Volume: 50μL
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use.
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有效期
- 12 months
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- GRIN1/NMDAR1 (GRIN1) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))
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别名
- Grin1
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背景
- Glutamate [NMDA] receptor subunit zeta-1,N-methyl-D-aspartate receptor subunit NR1, NMD-R1, Grin1,NMDA R1, Splice Variant C1 antibody detects NMDA R1receptor protein. The ion channels activated by glutamate that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA Receptors (NMDAR). The NMDAR plays an essential role in memory and neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death. There are a number of different splice variants of the NR1-Subunit. Differential splicing of three exons in the NR1-Subunit generates up to eight NR1-Subunit splice variants and 7 of these have been identified in cDNA libraries. These exons encode a 21 amino acid N-terminal domain (N1) and adjacent sequences in the C-terminus (C1 and C2). Splicing out the C2 cassette eliminates the first stop codon and produces a new reading frame that generates a new sequence of 22 amino acids (C2'). Considerable attention has been focused on the distribution and expression of these splice variants that may affect the functional properties and regulation of the NMDAR. Anti-NMDA R1, Splice Variant C1 Antibody is ideal for investigators involved in Neuroscience and Signal Transduction research.
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基因ID
- 24408
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NCBI登录号
- NP_058706
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UniProt
- P35439
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途径
- Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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