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NEUROD1 抗体 (N-Term)

Rockland 600-101-mn7s NEUROD1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
Rockland
产品编号 ABIN7540577
Supplier Product No.: 600-101-mn7s
发货至: 中国
  • 抗原 See all NEUROD1 抗体
    NEUROD1 (Neuronal Differentiation 1 (NEUROD1))
    抗原表位
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    N-Term
    适用
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    宿主
    • 89
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    • 1
    山羊
    克隆类型
    • 81
    • 16
    多克隆
    标记
    • 41
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    This NEUROD1 antibody is un-conjugated
    应用范围
    • 74
    • 41
    • 26
    • 26
    • 16
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    • 8
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    Western Blotting (WB), ELISA
    Supplier Product No.
    600-101-mn7s
    Supplier
    Rockland
    原理
    NEUROD1 Antibody
    交叉反应 (详细)
    This affinity purified antibody is directed against human NEUROD1.
    纯化方法
    The product was affinity purified from monospecific antiserum by immunoaffinity purification.
    过滤
    Sterile filtered
    免疫原
    Anti-NEUROD1 Antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to a N-terminal region of human Neurogenic differentiation factor 1 conjugated to Keyhole Limpet Hemocyanin (KLH).
    亚型
    IgG
    Top Product
    Discover our top product NEUROD1 Primary Antibody
  • 应用备注

    ELISA_Dilution: 1:10,000 - 1:50,000

    Western_Blot_Dilution: 5 μg/mL

    说明

    Anti-NEUROD1 Antibody has been tested in Western Blot. Expect a band at ~39.9 kDa in western blot using appropriate lysates or tissues. Positive control used rec. NEUROD1 protein or SCLC-21H whole cell lysates in WB.

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.
    有效期
    12 months
  • 抗原
    NEUROD1 (Neuronal Differentiation 1 (NEUROD1))
    别名
    NEUROD1 (NEUROD1 产品)
    背景
    Goat Anti-Neuronal Differentiation 1 Antibody, Neurogenic Helix-Loop-Helix Protein NEUROD, Class A Basic Helix-Loop-Helix Protein 3, Neurogenic Differentiation Factor 1, Beta-Cell E-Box Transactivator 2, NEUROD, BHLHa3, Basic Helix-Loop-Helix Transcription Factor, Neurogenic Differentiation 1, NeuroD1, BHLHA3, NeuroD, BETA2, BHF-1, MODY6,NEUROD1 (Neuronal Differentiation 1) gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. It acts as a transcriptional activator: mediates transcriptional activation by binding to E box-containing promoter consensus core sequences 5'-CANNTG-3'. NEUROD1 associates with the p300/CBP transcription coactivator complex to stimulate transcription of the secretin gene as well as the gene encoding the cyclin-dependent kinase inhibitor CDKN1A. Contributes to the regulation of several cell differentiation pathways, like those that promote the formation of early retinal ganglion cells, inner ear sensory neurons, granule cells forming either the cerebellum or the dentate gyrus cell layer of the hippocampus, endocrine islet cells of the pancreas and enteroendocrine cells of the small intestine. Together with PAX6 or SIX3, it is required for the regulation of amacrine cell fate specification. It is also required for dendrite morphogenesis and maintenance in the cerebellar cortex. NEUROD1 associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis. Anti-NEUROD1 is useful for researchers interested in Maturity-onset diabetes of the young Type 6, Diabetes mellitus noninsulin-dependent, as well as, developmental biology, DNA-binding transcription factor activity, and protein heterodimerization activity.
    基因ID
    4760
    NCBI登录号
    NP_002491
    UniProt
    Q13562
    途径
    Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis
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