NEUROD1 抗体 (N-Term)
Quick Overview for NEUROD1 抗体 (N-Term) (ABIN7540577)
抗原
See all NEUROD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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Supplier Product No.
- 600-101-mn7s
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Supplier
- Rockland
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原理
- NEUROD1 Antibody
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交叉反应 （详细）
- This affinity purified antibody is directed against human NEUROD1.
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纯化方法
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
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过滤
- Sterile filtered
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免疫原
- Anti-NEUROD1 Antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to a N-terminal region of human Neurogenic differentiation factor 1 conjugated to Keyhole Limpet Hemocyanin (KLH).
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亚型
- IgG
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anti-Neuronal Differentiation 1 (NEUROD1) (AA 26-91) antibody
NEUROD1 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 4G12B4 unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (AA 201-300) antibodyNEUROD1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3H8 unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (AA 26-91) antibodyNEUROD1 适用: 人, 小鼠, 猴 ELISA 宿主: 小鼠 Monoclonal 6E9G12 unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (AA 15-45) antibodyNEUROD1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (N-Term) antibodyNEUROD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (AA 15-45) antibodyNEUROD1 适用: 人 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (AA 15-45), (N-Term) antibodyNEUROD1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB02901 unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (AA 26-91) antibodyNEUROD1 适用: 人, 小鼠 WB, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (AA 21-120) antibodyNEUROD1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (AA 154-356) antibodyNEUROD1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA_Dilution: 1:10,000 - 1:50,000
Western_Blot_Dilution: 5 μg/mL
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说明
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Anti-NEUROD1 Antibody has been tested in Western Blot. Expect a band at ~39.9 kDa in western blot using appropriate lysates or tissues. Positive control used rec. NEUROD1 protein or SCLC-21H whole cell lysates in WB.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.
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有效期
- 12 months
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- NEUROD1 (Neuronal Differentiation 1 (NEUROD1))
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别名
- NEUROD1
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背景
- Goat Anti-Neuronal Differentiation 1 Antibody, Neurogenic Helix-Loop-Helix Protein NEUROD, Class A Basic Helix-Loop-Helix Protein 3, Neurogenic Differentiation Factor 1, Beta-Cell E-Box Transactivator 2, NEUROD, BHLHa3, Basic Helix-Loop-Helix Transcription Factor, Neurogenic Differentiation 1, NeuroD1, BHLHA3, NeuroD, BETA2, BHF-1, MODY6,NEUROD1 (Neuronal Differentiation 1) gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. It acts as a transcriptional activator: mediates transcriptional activation by binding to E box-containing promoter consensus core sequences 5'-CANNTG-3'. NEUROD1 associates with the p300/CBP transcription coactivator complex to stimulate transcription of the secretin gene as well as the gene encoding the cyclin-dependent kinase inhibitor CDKN1A. Contributes to the regulation of several cell differentiation pathways, like those that promote the formation of early retinal ganglion cells, inner ear sensory neurons, granule cells forming either the cerebellum or the dentate gyrus cell layer of the hippocampus, endocrine islet cells of the pancreas and enteroendocrine cells of the small intestine. Together with PAX6 or SIX3, it is required for the regulation of amacrine cell fate specification. It is also required for dendrite morphogenesis and maintenance in the cerebellar cortex. NEUROD1 associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis. Anti-NEUROD1 is useful for researchers interested in Maturity-onset diabetes of the young Type 6, Diabetes mellitus noninsulin-dependent, as well as, developmental biology, DNA-binding transcription factor activity, and protein heterodimerization activity.
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基因ID
- 4760
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NCBI登录号
- NP_002491
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UniProt
- Q13562
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途径
- Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis
抗原
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