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NEUROD1 抗体 (N-Term)

NEUROD1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB02901 unconjugated
产品编号 ABIN388765
发货至: 中国
  • 抗原 See all NEUROD1 抗体
    NEUROD1 (Neuronal Differentiation 1 (NEUROD1))
    抗原表位
    • 17
    • 16
    • 8
    • 8
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 15-45, N-Term
    适用
    • 73
    • 61
    • 51
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 85
    • 6
    克隆类型
    • 77
    • 14
    多克隆
    标记
    • 41
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This NEUROD1 antibody is un-conjugated
    应用范围
    • 74
    • 41
    • 26
    • 26
    • 16
    • 15
    • 13
    • 11
    • 8
    • 6
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This NeuroD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-45 amino acids from the N-terminal region of human NeuroD1.
    克隆位点
    RB02901
    亚型
    Ig Fraction
    Top Product
    Discover our top product NEUROD1 Primary Antibody
  • 应用备注
    IF: 1:10~50. IF: 1:100. WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    NEUROD1 (Neuronal Differentiation 1 (NEUROD1))
    别名
    NeuroD1 (NEUROD1 产品)
    别名
    BETA2 antibody, BHF-1 antibody, MODY6 antibody, NEUROD antibody, bHLHa3 antibody, Neurod antibody, neurod antibody, XNeuroD antibody, MGC82572 antibody, NEUROD1 antibody, ND1 antibody, beta2 antibody, bhf-1 antibody, neuro-D antibody, nrd antibody, neuroD antibody, neurod1 antibody, Beta2 antibody, neuronal differentiation 1 antibody, neurogenic differentiation 1 antibody, neuronal differentiation 1 S homeolog antibody, neuronal differentiation 1 L homeolog antibody, NEUROD1 antibody, Neurod1 antibody, neurod1.S antibody, neurod1 antibody, neurod1.L antibody
    背景
    NeuroD1 acts as a differentiation factor during neurogenesis. They are expressed transiently in a subset of neurons in the central and peripheral nervous systems at the time of their terminal differentiation. NeuroD1 is a basic helix-loop-helix (bHLH) protein contain 1 bHLH domain. NeuroD1 is a transcriptional activator, for efficient DNA binding it requires dimerization with another bHLH protein. It was reported that NeuroD1 involves heterodimerization with the ubiquitous bHLH protein E47, and regulates insulin gene expression by binding to a critical E-box motif on the insulin promoter. Defects in NEUROD1 causes maturity onset diabetes of the young type VI. MODY6 is a form of non-insulin-dependent diabetes mellitus (NIDDM) characterized by an autosomal dominant mode of inheritance, onset during young adulthood and a primary defect in insulin secretion.
    分子量
    39920
    基因ID
    4760
    NCBI登录号
    NP_002491
    UniProt
    Q13562
    途径
    Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis
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