UCHL1 抗体
(1 reference)
Quick Overview for UCHL1 抗体 (ABIN7540520)
抗原
See all UCHL1 抗体适用
宿主
克隆类型
标记
应用范围
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Supplier Product No.
- 200-901-e52
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Supplier
- Rockland
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原理
- Ubiquitin Hydrolase (UCHL1) Antibody
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交叉反应 （详细）
- Anti-UCHL1 antibody is directed against human UCHL1 proteins.
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纯化方法
- The antibody was purified from chicken eggs as an IgY fraction.
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免疫原
- Anti-UCHL1 Antibody was produced in chicken by repeated immunizations with recombinant full length human UCHL1 extensively purified from E. coli.
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亚型
- IgG
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anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) (AA 2-223) antibody
UCHL1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) (AA 2-223) antibodyUCHL1 适用: 小鼠 WB, IHC, FACS, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) (AA 2-223) antibodyUCHL1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) antibodyUCHL1 适用: 人, 大鼠 WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal rUCHL1-775 unconjugated Recombinant Antibody
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) (AA 59-223) antibodyUCHL1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) (AA 187-216), (C-Term) antibodyUCHL1 适用: 人, 大鼠, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB7379 unconjugated
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) antibodyMicroarray verified UCHL1 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB215939 unconjugated
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) (AA 1-223) antibodyUCHL1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B8-4D2 unconjugated
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) antibodyUCHL1 适用: 人, 大鼠, 小鼠, Cow, Pig WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal 31A3 unconjugated
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) (AA 16-46), (N-Term) antibodyUCHL1 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB04183 unconjugated
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应用备注
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ELISA_Dilution: 1:25,000
IF_Microscopy_Dilution: 1:500
Western_Blot_Dilution: 1:2500
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说明
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Suggested Applications: Other
Anti-Ubiquitin Hydrolase antibody is tested for use in Western Blotting and IF. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 24 kDa in size corresponding to the UCHL1 proteins in Western blots in the appropriate cell lysate or extract. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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: "Over-expression of Oct4 and Sox2 transcription factors enhances differentiation of human umbilical cord blood cells in vivo." in: Biochemical and biophysical research communications, Vol. 451, Issue 4, pp. 503-9, (2014) (PubMed).
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: "Over-expression of Oct4 and Sox2 transcription factors enhances differentiation of human umbilical cord blood cells in vivo." in: Biochemical and biophysical research communications, Vol. 451, Issue 4, pp. 503-9, (2014) (PubMed).
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- UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))
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别名
- UCHL1
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背景
- UCH-L1, Neuron cytoplasmic protein 9.5, PGP 9.5, Ubiquitin thioesterase L1,UCHL1 antibody recognizes Ubiquitin C-terminal hydrolase 1 (UCHL1) which is also known as ubiquitin carboxyl esterase L1, ubiquitin thiolesterase, neuron-specific protein PGP9.5 and Park5. It was originally identified as a major component of the neuronal cytoplasm from 2-dimensional gel analysis of brain tissues, and was given the name PGP9.5. It was later found that ubiquitin C-terminal hydrolase enzyme activity was associated with the PGP9.5 protein. The ubiquitin C-terminal hydrolases cleave ubiquitin from other molecules. Regulation of the ubiquitin pathway is very important and many disease states are associated with defects in this pathway. Genetic knockout of UCHL1 in mice results in a motor neuron degeneration similar to the spontaneous gracile axonal dystrophy (gad) mutant mice. Point mutations in the UCHL1 gene are associated with some forms of human Parkinson's disease. Since UCHL1 is heavily expressed in neurons, it is released in large amounts following injury or degeneration, so the detection of UCHL1 in CSF and other bodily fluids can be used as a biomarker. Therefore, UCHL1 antibody is ideal for investigators involved in neuronal disorders and, more generally in Neuroscience.
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基因ID
- 7345
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UniProt
- P09936
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途径
- Feeding Behaviour
抗原
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