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FLIP 抗体 (C-Term)

This anti-FLIP antibody is a 兔 多克隆 antibody detecting FLIP in WB, ELISA, IHC, IF 和 FM. Suitable for 人.
Rockland
产品编号 ABIN7540512
Supplier Product No.: 200-401-983
发货至: 中国

Quick Overview for FLIP 抗体 (C-Term) (ABIN7540512)

抗原

See all FLIP (CFLAR) 抗体
FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

适用

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宿主

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克隆类型

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多克隆

标记

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This FLIP antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Fluorescence Microscopy (FM)
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    C-Term

    Supplier Product No.

    200-401-983

    Supplier

    Rockland

    原理

    FLIP Alpha Antibody

    纯化方法

    Anti-FLIP Antibody is affinity chromatography purified via peptide column. The product was purified from monospecific antiserum by DEAE ion exchange chromatography.

    过滤

    Sterile filtered

    免疫原

    FLIP Antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids near the carboxyl terminus of the human FLIPalpha/FLIPL protein.

    亚型

    IgG
  • 应用备注

    ELISA_Dilution: User Optimized

    IF_Microscopy_Dilution: 10 μg/mL

    Western_Blot_Dilution: 0.5-1 μg/mL

    Other: ICC: 10 μg/mL

    说明

    FLIP Antibody has been tested for use in ELISA, western blotting, Immunofluorescence, and Immunohistochemistry.  HeLa whole cell lysate can be used as a positive control in western blotting, and a band at approximately 55 kDa is expected. Specific conditions for reactivity should be optimized by the end user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.02 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    有效期

    12 months
  • 抗原

    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

    别名

    CFLAR

    背景

    C FLIP antibody, c FLIPL antibody, c FLIPR antibody, c FLIPS antibody, CASH antibody, CASP8 and FADD like apoptosis regulator antibody, CASP8 and FADD like apoptosis regulator precursor antibody, CASP8 antibody, CASP8AP1 antibody, FLIP-L, CLARP1, MRIT alpha-1, CASH alpha, I-FLICE 1, FLAME-1 gamma,Apoptosis is related to many diseases and is induced by a family of cell death receptors and their ligands.  Cell death signals are transduced by death domain (DD)-containing adapter molecules and members of the ICE/CED-3 protease family.  Caspases-8 (FLICE) and -10 (FLICE2) are two pivotal members in the ICE/CED-3 protease family.  FLICE-inhibitory proteins were identified in virus and human and designated v-FLIPs and FLIP, respectively.  The human FLIP was also cloned by several labs independently and termed Casper, I-FLICE, FLAME-1, CASH and CLARP.  FLIP contains two death effector domains (DEDs) and a caspase-like domain.  FLIP interacts with adapter protein FADD and caspase-8 and -10, and potently inhibits apoptosis induced by all known death receptors.  Four splice variants of FLIPs have been identified and termed FLIP α, β, γ, and δ, respectively. Anti-FLIP antibody is ideal for investigators involved in Apoptosis, Cytokines and Growth factor research.

    基因ID

    8837, 187608571

    UniProt

    O15519

    途径

    Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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