Galectin 9 抗体 (PE)
Quick Overview for Galectin 9 抗体 (PE) (ABIN7540454)
抗原
See all Galectin 9 (LGALS9) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu Galectin-9 PE
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特异性
- The mouse monoclonal antibody 9M1-3 recognizes an epitope within C terminus of human galectin-9, a glycan-binding protein expressed mainly on activated Th cells and FoxP3+ Treg cells.
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纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- recombinant M-type splicing variant of human galectin 9
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亚型
- IgG1 kappa
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应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. Intracellular staining.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- Galectin 9 (LGALS9) (Lectin, Galactoside-Binding, Soluble, 9 (LGALS9))
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别名
- Galectin-9
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背景
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NCBI Full Gene Name: galectin 9
Description: Galectin-9 is a glycan-binding protein, which is expressed in three main isoforms of 49 aa, 27 aa, and 15 aa. It can be detected on the cell surface, as well as intracellularly, or in a secreted form. On the cell surface, galectin-9 plays roles in contacts with other cells and with extracellular matrix. It is expressed on multiple cell types, but mainly on Treg cells, activated Th cells and some cancers. Its secreted form acts like a cytokine with immunomodulatory and immunosuppresive functions. Massive and inadequate production of galectin-9, associated with some viral infections or cancers, can counteract immune reactions to these illnesses. High levels of galectin-9 expression lead to poor prognosis of cancer patients.
Other names: HUAT, LGalS9A, LEG9
Gene name: LGALS9
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基因ID
- 3965
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UniProt
- O00182
抗原
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