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Galectin 9 抗体 (Internal Region)

LGALS9 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6262950
发货至: 中国
  • 抗原 See all Galectin 9 (LGALS9) 抗体
    Galectin 9 (LGALS9) (Lectin, Galactoside-Binding, Soluble, 9 (LGALS9))
    抗原表位
    • 16
    • 8
    • 8
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 72
    • 45
    • 19
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 88
    • 12
    • 1
    克隆类型
    • 86
    • 13
    • 2
    多克隆
    标记
    • 51
    • 17
    • 9
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Galectin 9 antibody is un-conjugated
    应用范围
    • 80
    • 39
    • 35
    • 26
    • 14
    • 12
    • 11
    • 10
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    Galectin-9 Antibody detects endogenous levels of total Galectin-9.
    预测反应
    Pig,Bovine
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human Galectin-9, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product LGALS9 Primary Antibody
  • 应用备注
    WB 1:500-1:2000C, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    Galectin 9 (LGALS9) (Lectin, Galactoside-Binding, Soluble, 9 (LGALS9))
    别名
    LGALS9 (LGALS9 产品)
    别名
    huat antibody, lgals9a antibody, ecalectin antibody, galectin-9 antibody, Lgals9 antibody, wu:fd20c09 antibody, zgc:111833 antibody, LGALS9 antibody, AA407335 antibody, AI194909 antibody, AI265545 antibody, LGALS35 antibody, Lgals5 antibody, gal-9 antibody, HUAT antibody, LGALS9A antibody, UAT antibody, UATP.I antibody, galectin 9 L homeolog antibody, galectin 9 antibody, lectin, galactoside-binding, soluble, 9 (galectin 9)-like 3 antibody, lectin, galactose binding, soluble 9 antibody, lgals9.L antibody, lgals9 antibody, lgals9l3 antibody, LGALS9 antibody, Lgals9 antibody
    背景

    Description: Binds galactosides (PubMed:18005988). Has high affinity for the Forssman pentasaccharide (PubMed:18005988). Ligand for HAVCR2/TIM3 (PubMed:16286920). Binding to HAVCR2 induces T-helper type 1 lymphocyte (Th1) death (PubMed:16286920). Also stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth (By similarity). Ligand for P4HB, the interaction retains P4HB at the cell surface of Th2 T-helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration (PubMed:21670307). Ligand for CD44, the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function (By similarity). Promotes ability of mesenchymal stromal cells to suppress T-cell proliferation (PubMed:23817958). Expands regulatory T-cells and induces cytotoxic T-cell apoptosis following virus infection (PubMed:20209097). Activates ERK1/2 phosphorylation inducing cytokine (IL-6, IL-8, IL-12) and chemokine (CCL2) production in mast and dendritic cells (PubMed:24465902, PubMed:16116184). Inhibits degranulation and induces apoptosis of mast cells (PubMed:24465902). Induces maturation and migration of dendritic cells (PubMed:25754930, PubMed:16116184). Inhibits natural killer (NK) cell function (PubMed:23408620). Can transform NK cell phenotype from peripheral to decidual during pregnancy (PubMed:25578313). Astrocyte derived galectin-9 enhances microglial TNF production (By similarity). May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus. May provide the molecular basis for urate flux across cell membranes, allowing urate that is formed during purine metabolism to efflux from cells and serving as an electrogenic transporter that plays an important role in renal and gastrointestinal urate excretion (By similarity). Highly selective to the anion urate (By similarity).

    Gene: LGALS9

    分子量
    40 kDa
    基因ID
    3965
    UniProt
    O00182
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