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CD7 抗体 (Biotin)

This anti-CD7 antibody is a 小鼠 单克隆 antibody detecting CD7 in FACS. Suitable for 人.
产品编号 ABIN7540449
发货至: 中国

Quick Overview for CD7 抗体 (Biotin) (ABIN7540449)

抗原

See all CD7 抗体
CD7

适用

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宿主

  • 125
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小鼠

克隆类型

  • 135
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单克隆

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This CD7 antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS)

克隆位点

124-1D1
  • 原理

    Anti-Hu CD7 Biotin

    特异性

    The mouse monoclonal antibody 124-1D1 recognizes an extracellular epitope of CD7, a 40 kD type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia.

    纯化方法

    Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.

    亚型

    IgG1 kappa
  • 应用备注

    Flow cytometry: Recommended dilution: 1-5 μg/mL.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • 抗原

    CD7

    别名

    CD7

    背景

    NCBI Full Gene Name: CD7 Molecule

    Description: CD7, also known as gp40, is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion. A ligand of CD7, epithelial cell secreted protein K12, is produced in thymus to regulate thymocyte signaling and cytokine release. In lung microvascular endothelial cells CD7 serves as an IgM Fc receptor. Expression of CD7 is an important marker used in leukemia diagnostics.

    Other names: GP40, TLA, TP41, LEU-9

    Gene name: CD7

    基因ID

    924

    UniProt

    P09564

    途径

    Cell-Cell Junction Organization
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