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CD34 抗体 (Biotin)

This anti-CD34 antibody is a 小鼠 单克隆 antibody detecting CD34 in FACS, WB, IHC (p), IP 和 IHC (fro). Suitable for 人 和 Non-Human Primate.
产品编号 ABIN7540437
发货至: 中国

Quick Overview for CD34 抗体 (Biotin) (ABIN7540437)

抗原

See all CD34 抗体
CD34

适用

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人, Non-Human Primate

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD34 antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

QBEnd-10
  • 原理

    Anti-Hu CD34 Biotin

    特异性

    The antibody QBEnd-10 reacts with an extracellular class II epitope on CD34, a 110-115 kDa monomeric transmembrane phosphoglycoprotein expressed on hematopoietic progenitors cells and on the most pluripotential stem cells, it is gradually lost on progenitor cells. This antibody has been also used as an endothelial marker.

    无交叉反应

    Cow, 犬, 大鼠, 绵羊

    纯化方法

    Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.

    免疫原

    Human endothelial vesicles

    亚型

    IgG1
  • 应用备注

    Flow cytometry: Recommended dilution: 1-5 μg/mL.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • 抗原

    CD34

    别名

    CD34

    背景

    NCBI Full Gene Name: CD34 Molecule

    Description: CD34 is a highly glycosylated monomeric 111-115 kDa surface protein, which is present on many stem cell populations. It is a well established stem cell marker, though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions.

    Gene name: CD34

    基因ID

    947

    UniProt

    P28906
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