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CD163 抗体 (Biotin)

This anti-CD163 antibody is a 小鼠 单克隆 antibody detecting CD163 in WB, FACS, IP 和 IHC (fro). Suitable for 人.
产品编号 ABIN7540423
发货至: 中国

Quick Overview for CD163 抗体 (Biotin) (ABIN7540423)

抗原

See all CD163 抗体
CD163

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD163 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

GHI-61
  • 原理

    Anti-Hu CD163 Biotin

    特异性

    The mouse monoclonal antibody GHI/61 recognizes an extracellular epitope CD163, an approximately 130 kDa high affinity scavenger receptor expressed mainly on monocytes and macrophages, which binds hemoglobin-haptoglobin complex.

    纯化方法

    Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.

    免疫原

    Hairy cell leukemia cells

    亚型

    IgG1 kappa
  • 应用备注

    Flow cytometry: Recommended dilution: 1-5 μg/mL.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • 抗原

    CD163

    别名

    CD163

    背景

    NCBI Full Gene Name: CD163 Molecule

    Description: CD163, also known as M130, is a member of the scavenger receptor family, accounting for the clearance of hemoglobin-haptoglobin complexes during limited hemolysis, which protects the body, in particular the kidneys, against heme-mediated oxidative damages. It does not have measurable affinity for noncomplexed hemoglobin or haptoglobin. Immunomodulatory role of CD163 has been postulated. CD163 is expressed by cells of the monocyte-macrophage lineage and its extracellular part also circulates in plasma as a soluble protein, especially during sepsis and other conditions affecting macrophage activity, when its level may raise manyfold.

    Other names: MM130, SCARI1

    Gene name: CD163

    基因ID

    9332

    UniProt

    Q86VB7
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