CSF3R 抗体 (APC)
Quick Overview for CSF3R 抗体 (APC) (ABIN7540414)
抗原
See all CSF3R 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD114 APC
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特异性
- The mouse monoclonal antibody LMM741 recognizes an extracellular epitope of CD114 (colony stimulating factor 3 receptor), a 130 kDa transmembrane glycoprotein expressed on granulocytes and their differentiation stages, on monocytes, platelets, endothelial cells and placenta. It is absent from lymphocytes and erythrocytes.
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无交叉反应
- 小鼠
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纯化方法
- Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- CHO cells transfected with human CD114
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亚型
- IgG1 kappa
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anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 26-138) antibody
CSF3R 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 25-187) antibodyCSF3R 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 8F8B12 unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 271-428) antibodyCSF3R 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 25-187) antibodyCSF3R 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3G10G2 unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 117-337) antibodyCSF3R 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 101-200) antibodyCSF3R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 1-836) antibodyCSF3R 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) antibodyCSF3R 适用: 人 FACS 宿主: 小鼠 Monoclonal LMM741 unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 252-280) antibodyCSF3R 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23568 unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 259-288), (Middle Region) antibodyCSF3R 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))
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别名
- CD114
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背景
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NCBI Full Gene Name: colony stimulating factor 3 receptor
Description: CD114 / G-CSFR (granulocyte colony-stimulating factor receptor, also known as CSF3R) is a type I transmembrane glycoprotein which upon binding of its ligand (G-CSF, granulocyte colony-stimulating factor) homodimerizes and activates signaling transduction to mediate cell proliferation, survival, and differentiation. It is expressed by granulocytes at all stages of their differentiation, as well as by monocytes, dendritic cells, and mature platelets. Among non-hematopoietic cells, it is expressed e.g. by endothelial cells, placenta, trophoblasts, and many tumor cell lines. This antigen is a target for stem cell mobilization for blood stem cell transplantation, for enhancing recovery of myelopoiesis following chemotherapy and in the treatment of patients with severe chronic neutropenia.
Other names: GCSFR, CSF3R, SCN7
Gene name: CSF3R
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基因ID
- 1441
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UniProt
- Q99062
抗原
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