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Galectin 3 抗体 (APC)

The 大鼠 单克隆 anti-Galectin 3 antibody is suitable to detect Galectin 3 in samples from 人 和 小鼠. It has been validated for FACS 和 ICFC.
产品编号 ABIN7540407
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Galectin 3 抗体 (APC) (ABIN7540407)

抗原

See all Galectin 3 (LGALS3) 抗体
Galectin 3 (LGALS3)

适用

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人, 小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This Galectin 3 antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)

克隆位点

M3-38
  • 原理

    Anti-Galectin-3 APC

    产品特性

    The rat monoclonal antibody M3/38 recognizes an epitope within amino acids 40-100 in N-terminal domain of murine galectin 3, a 35 kDa lectin expressed both intracellularly, and after its secretion also on the cell surface.

    纯化方法

    Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    murine galectin-3

    亚型

    IgG2a, kappa
  • 应用备注

    Flow cytometry: Recommended dilution: 1-5 μg/mL.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze,Protect from prolonged exposure to light

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原

    Galectin 3 (LGALS3)

    别名

    Galectin-3

    背景

    NCBI Full Gene Name: lectin, galactose binding, soluble 3

    Description: Galectin-3 is a galactose-binding lectin, which modulates intercellular interactions and interactions of the cell with ECM, as well as it is a nuclear protein and a component of inner mitochondrial membrane. Galectin-3 binds IgE, and takes part in formation of immunological synapse. It is detected cytoplasmatically in adenomas and carcinomas by immunohistochemistry. It is expressed in colonic and intestinal epithelium, papillary and follicular carcinomas, neoplastic astrocytes, inflammatory macrophages, and some lymphocytes. Upregulation of galectin-3 is involved in cancer progression and metastasis.

    Other names: Mac-2, GBP, Gal-3, L-34

    Gene name: Lgals3

    基因ID

    16854

    UniProt

    P16110

    途径

    RTK signaling
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