Recombinant CD8 抗体 (Extracellular Domain) (Atto 647N)
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Quick Overview for Recombinant CD8 抗体 (Extracellular Domain) (Atto 647N) (ABIN7540335)
抗原
See all CD8 抗体抗体类型
片段
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Extracellular Domain
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Expression System
- E.coli
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原理
- Anti-CD8 (Human) LIMAAbody® is a carefully developed and validated polyclonal nanobody (single-domain antibody) binding to human CD8 highly suitable for tissue stainings.
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品牌
- LIMAAbody®
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特异性
- Detects endogenous levels of total human CD8 alpha protein.
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交叉反应 （详细）
- not analysed
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产品特性
- VHH protein tag: C-terminal (6x) His-Tag
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纯化方法
- Affinity-purified antibody fragment.
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免疫原
- Recombinant protein containing the extracellular domain of human CD8 protein.
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anti-CD8 (CD8) (AA 51-150) antibody
CD8 适用: 人, 小鼠, 大鼠 FACS, IHC (fro), WB, ELISA, IHC (p), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-CD8 (CD8) antibody (PE)CD8 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-31 PE
anti-CD8 (CD8) (AA 22-187) antibodyCD8 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD8 (CD8) (AA 135-235) antibodyCD8 适用: 人 IHC 宿主: 兔 Monoclonal 008R unconjugated Recombinant Antibody
anti-CD8 (CD8) antibodyCD8 适用: 人 FACS, IP, MS 宿主: 小鼠 Monoclonal MEM-31 unconjugated
anti-CD8 (CD8) antibody (Biotin)CD8 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal MEM-31 Biotin
anti-CD8 (CD8) antibody (FITC)CD8 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-31 FITC
anti-CD8 (CD8) antibody (PE)CD8 适用: Cat FACS 宿主: 小鼠 Monoclonal fCD8 PE
anti-CD8 (CD8) antibody (APC)CD8 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-31 APC
anti-CD8 (CD8) antibody (PerCP)CD8 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-31 PerCP
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应用备注
- Immunofluorescence: 10 μg/mL (frozen sections), 10 μg/mL (cell culture), 20 μg/mL (wholemount), 10 μg/mL (FACS)
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说明
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VHH protein tag: C-terminal (6x) His-Tag
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, 0.02% sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze.
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储存条件
- 4 °C
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储存方法
- Upon receipt store at 4°C. Stable for 6 months. Do not freeze.
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有效期
- 6 months
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- CD8
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别名
- CD8
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背景
- CD8, known as Cluster of Differentiation 8, forms a disulphide-linked heterodimer comprising unrelated α and β subunits. Each subunit, characterized as a glycoprotein, is structured with a single extracellular Ig-like domain, a polypeptide linker, a transmembrane component, and a concise cytoplasmic tail. Within T cells, CD8 serves as the co-receptor alongside the T cell receptor (TCR). These distinct structures collaboratively identify the Antigen-Major Histocompatibility Complex (MHC). Specifically, the interaction occurs between the Ig-like domain of CD8α and the α3-domain of the MHC class I molecule. CD8 plays a pivotal role in ensuring the specificity of the TCR-antigen interaction, extending the duration of contact between the T cell and the antigen-presenting cell. Moreover, the α chain of CD8 recruits the tyrosine kinase Lck, an indispensable component for initiating T cell activation .
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分子量
- 26 kDa
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NCBI登录号
- NP_001759
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UniProt
- P01732
抗原
-
